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Prevalence and risk factors of type 2 diabetes in middle-aged women in Northern Vietnam

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Abstract

The existing gender difference in prevalence of type 2 diabetes may be explained partly by women’s reproductive patterns. A cross-sectional study was designed to investigate the prevalence of type 2 diabetes, prediabetes, and their association with reproductive patterns, socio-economic status, and anthropometric measures in Vietnamese women. Potential risk factors for the conditions were analyzed using multivariate logistic regression in the adjusted model, taken into account the influences of the reproductive patterns (age at menarche and menopause, year since menopause, number of children, and newborn weight), obesity-related measures, socio-economic status, and lifestyle-related factors. The age-adjusted prevalences of prediabetes and type 2 diabetes were 10.1 and 4.7 %, respectively. The prevalence of diabetes increased with age and reached a peak in the 60–64 group. Systolic blood pressure, waist–hip ratio, and family history of diabetes were the most significant risk factors for type 2 diabetes. The adjusted analysis model indicated that women with early menopause (45 years of age) were 3.4-fold and 2.7-fold more likely to suffer from type 2 diabetes and prediabetes, respectively, in comparison to women with normal age at menopause. More attention should be given to elderly women with early menopause, elevated systolic blood pressure, and increased obesity-related measures, who are at high risk of prediabetes and type 2 diabetes.

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References

  1. Global burden of diabetes. Diabetes Atlas, 6th ed. International Diabetes Federation. 2013. http://www.idf.org/diabetesatlas. Accessed 25 Aug 2014.

  2. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87:4–14.

    Article  CAS  PubMed  Google Scholar 

  3. Binh VT, Uoc KH. Epidemiology of diabetes in Vietnam: treatment methods and preventive measures. Hanoi: Hanoi Medical Publisher; 2005.

    Google Scholar 

  4. Vietnam Ministry of Health, National Hospital of Endocrinology. Annual Report of the National Programs for Control of Diabetes in 2012. Hanoi; 2013. pp. 16.

  5. Choi SE, Liu M, Palaniappan LP, Wang EJ, Wong ND. Gender and ethnic differences in the prevalence of type 2 diabetes among Asian subgroups in California. J Diabetes Complications. 2013;27:429–35.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Hilawe EH, Yatsuya H, Kawaguchi L, Aoyama A. Differences by sex in the prevalence of diabetes mellitus, impaired fasting glycaemia and impaired glucose tolerance in sub-Saharan Africa: a systematic review and meta-analysis. Bull World Health Organ. 2013;91:671–82.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Bellamy L, Casas JP, Hingorani AD, Williams D. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet. 2009;373:1773–9.

    Article  CAS  PubMed  Google Scholar 

  8. Stockl D, Doring A, Peters A, Thorand B, Heier M, Huth C, et al. Age at menarche is associated with prediabetes and diabetes in women (aged 32–81 years) from the general population: the KORA F4 study. Diabetologia. 2012;13:681–8.

    Article  Google Scholar 

  9. He C, Zhang C, Hunter DJ, Hankinson SE, Buck Louis GM, Hediger ML, et al. Age at menarche and risk of type 2 diabetes: results from 2 large prospective cohort studies. Am J Epidemiol. 2010;13:334–44.

    Article  Google Scholar 

  10. Qiu C, Chen H, Wen J, Zhu P, Lin F, Huang B, et al. Associations between age at menarche and menopause with cardiovascular disease, diabetes, and osteoporosis in Chinese women. J Clin Endocrinol Metab. 2013;98:1612–21.

    Article  CAS  PubMed  Google Scholar 

  11. Brand JS, van der Schouw YT, Onland-Moret NC, Sharp SJ, Ong KK, Khaw KT, et al. Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study. Diabetes Care. 2013;36:1012–9.

    Article  PubMed  PubMed Central  Google Scholar 

  12. He L, Tang X, Li N, Wu YQ, Wang JW, Li JR, et al. Menopause with cardiovascular disease and its risk factors among rural Chinese women in Beijing: a population-based study. Maturitas. 2012;72:132–8.

    Article  CAS  PubMed  Google Scholar 

  13. Di Donato P, Giulini NA, Bacchi Modena A, Cicchetti G, Comitini G, Gentile G, et al. Gruppo di Studio Progetto Menopausa Italia: Risk factors for type 2 diabetes in women attending menopause clinics in Italy: a cross-sectional study. Climacteric. 2005;8:287–93.

    Article  PubMed  Google Scholar 

  14. Chang CJ, Wu CH, Yao WJ, Yang YC, Wu JS, Lu FH. Relationships of age, menopause and central obesity on cardiovascular disease risk factors in Chinese women. Int J Obes. 2000;24:1699–704.

    Article  CAS  Google Scholar 

  15. Heianza Y, Arase Y, Kodama S, Hsieh SD, Tsuji H, Saito K, et al. Effect of postmenopausal status and age at menopause on type 2 diabetes and prediabetes in Japanese individuals: Toranomon Hospital Health Management Center Study 17 (TOPICS 17). Diabetes Care. 2013;36:4007–14.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Duc Son LN, Kusama K, Hung NT, Loan TT, Chuyen NV, Kunii D, et al. Prevalence and risk factors for Diabetes in Ho Chi Minh City, Vietnam. Diabetic Med. 2004;21:371–6.

    Article  CAS  PubMed  Google Scholar 

  17. Quang Binh T, Tran Phuong P, Thi Nhung B, Dinh Thoang D, Van Thang P, Khanh Long T, et al. Prevalence and correlates of hyperglycemia in a rural population, Vietnam: implications from a cross-sectional study. BMC Public Health. 2012;12:939.

    Article  PubMed  PubMed Central  Google Scholar 

  18. General Statistics Office. The 2009 Vietnam population and housing census: Completed results. Hanoi: Statistical Publishing House; 2012. http://www.gso.gov.vn. Accessed 20 Jul 2014.

  19. World Health Organization. Definition and diagnosis of diabetes mellitus and intermediate hyperglycemia: report of a WHO consultation. Geneva: World Health Organization; 2006.

    Google Scholar 

  20. WHO Expert Consultation. Appropriate body–mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004;363:157–63.

    Article  Google Scholar 

  21. International Obesity Task Force (on behalf of the Steering Committee). The Asia–Pacific perspective: redefining obesity and its treatment. Sydney: Western Pacific Region. Health Communications Australia. 2002.

    Google Scholar 

  22. Ambady R, Chamukuttan S, Ananth S, Arun N. Trends in prevalence of diabetes in Asian countries. World J Diabetes. 2012;3:110–7.

    Article  Google Scholar 

  23. Chan JC, Malik V, Jia W, Kadowaki T, Yajnik CS, Yoon KH, et al. Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA. 2009;301:2129–40.

    Article  CAS  PubMed  Google Scholar 

  24. Ta MT, Nguyen KT, Nguyen ND, Campbell LV, Nguyen TV. Identification of undiagnosed type 2 diabetes by systolic blood pressure and waist–to–hip ratio. Diabetologia. 2010;53:2139–46.

    Article  CAS  PubMed  Google Scholar 

  25. Ramachandran A, Snehalatha C. Current scenario of diabetes in India. J Diabetes. 2009;1:18–28.

    Article  PubMed  Google Scholar 

  26. Upadhyay RP, Misra P, Chellaiyan VG, Das TK, Adhikary M, Chinnakali P, et al. Burden of diabetes mellitus and prediabetes in tribal population of India: a systematic review. Diabetes Res Clin Pract. 2013;102:1–7.

    Article  PubMed  Google Scholar 

  27. Saeed KMI, Asghar RJ, Sahak MN, Ansari J. Prevalence and risk factors associated with diabetes mellitus among Kabul citizens-Afghanistan, 2012. Int J Diabetes Dev Ctries. 2015. doi:10.1007/s13410-014-0270-3.

    Google Scholar 

  28. Shrestha UK, Singh DL, Bhattarai MD. The prevalence of hypertension and diabetes defined by fasting and 2-h plasma glucose criteria in urban Nepal. Diabet Med. 2006;23:1130–5.

    Article  CAS  PubMed  Google Scholar 

  29. Aekplakorn W, Chariyalertsak S, Kessomboon P, Sangthong R, Inthawong R, Putwatana P, et al. Prevalence and management of diabetes and metabolic risk factors in Thai adults: the Thai National Health Examination Survey IV, 2009. Diabetes Care. 2011;34:1980–5.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Zhang YH, Ma WJ, Thomas GN, Xu YJ, Lao XQ, Xu XJ, et al. Diabetes and pre–diabetes as determined by glycated haemoglobin a1c and glucose levels in a developing southern Chinese population. PLoS ONE. 2012;7:e37260. doi:10.1371/journal.pone.0037260.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Sekikawa A, Eguchi H, Tominaga M, Igarashi K, Abe T, Manaka H, et al. Prevalence of type 2 diabetes mellitus and impaired glucose tolerance in a rural area of Japan: the Funagata Diabetes Study. J Diabetes Complications. 2006;14:78–83.

    Article  Google Scholar 

  32. Kim DJ. The epidemiology of diabetes in Korea. Diabetes Metab J. 2011;35:303–8.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Ho-Pham LT, Lai TQ, Nguyen ND, Barrett-Connor E, Nguyen TV. Similarity in percent body fat between white and Vietnamese women: implication for a universal definition of obesity. Obesity (Silver Spring). 2010;18:1242–6.

    Article  Google Scholar 

  34. Lin PY, Nhung BT, Khan NC, Sarukura N, Kunii D, Sakai T, et al. Effect of Vietnamese common diet on postprandial blood glucose level in adult females. J Nutr Sci Vitaminol (Tokyo). 2007;53:247–52.

    Article  CAS  Google Scholar 

  35. Choi JY, Ha HS, Kwon HS, Lee SH, Cho HH, Yim HW, et al. Characteristics of metabolically obese, normal-weight women differ by menopause status: the Fourth Korea National Health and Nutrition Examination Survey. Menopause. 2013;20:85–93.

    Article  PubMed  Google Scholar 

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Acknowledgments

This study was supported by Vietnam’s National Foundation for Science and Technology Development (NAFOSTED), grant no. 106.99.140.09 from the Ministry of Science and Technology, Vietnam. The authors would like to thank Assoc. Prof. Le Danh Tuyen and Assoc. Prof. Nguyen Do Huy for the kind help and support. We acknowledge all the participants and the health staff of the Hai Duong Medical Technical University for their cooperation and assistance.

Conflict of interest

The authors declare no conflict of interest.

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Authors and Affiliations

  1. Department of Immunology and Molecular Biology, National Institute of Hygiene and Epidemiology, 1 Yersin, Hanoi, Vietnam

    Tran Quang Binh

  2. National Institute of Nutrition, 48B Tang Bat Ho Street, Hanoi, Vietnam

    Bui Thi Nhung

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  1. Tran Quang Binh
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Correspondence to Tran Quang Binh.

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Binh, T.Q., Nhung, B.T. Prevalence and risk factors of type 2 diabetes in middle-aged women in Northern Vietnam. Int J Diabetes Dev Ctries 36, 150–157 (2016). https://doi.org/10.1007/s13410-015-0372-6

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