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Status of zinc and magnesium levels in type 2 diabetes mellitus and its relationship with glycemic status

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Abstract

Diabetes mellitus (DM) is associated with alterations in the metabolism of zinc (Zn) and magnesium (Mg). The aim of the present study was to estimate the serum levels of these trace elements in patients with type 2 diabetes in relation to their glycemic status. Eighty seven type 2 diabetics & 30 apparently healthy sex and age matched control subjects were selected for the study. S-Zn and S-Mg levels were significantly low in type 2 diabetes patients. The serum levels of glucose were negatively correlated with serum levels of Zn and Mg of diabetic subjects. The low serum levels of Zn and Mg in diabetics compared to control subjects may be due to the poor glycemic control. Our study shows S-Zn & S-Mg levels are inversely related to glycemic status (HbA1C) of type 2 diabetics.

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Contributor’s details

Satwika Sinha- She designed the study, performed the experiments, did acquisition of data or analysis and interpretation of data and prepared the manuscript.

Sukanta Sen- He performed the literature search, assisted in supervised the data analysis, edited and reviewed the manuscript.

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Authors and Affiliations

  1. Department of Biochemistry, Calcutta National Medical College, Kolkata, 700014, India

    Satwika Sinha

  2. Department of Clinical & Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, 700073, India

    Sukanta Sen

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  1. Satwika Sinha
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Correspondence to Satwika Sinha.

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Sinha, S., Sen, S. Status of zinc and magnesium levels in type 2 diabetes mellitus and its relationship with glycemic status. Int J Diabetes Dev Ctries 34, 220–223 (2014). https://doi.org/10.1007/s13410-014-0196-9

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  • DOI: https://doi.org/10.1007/s13410-014-0196-9

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