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Effect of Egyptian Attapulgite Clay on the Properties of PVA-HES–Clay Nanocomposite Hydrogel Membranes for Wound Dressing Applications

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Abstract

In this study, attapulgite clay was extracted from North Western desert of Borg El-Arab, Egypt. The pristine clay was purified and treated before further use. The mineralogical composition of pristine clay was investigated by TEM, SEM, XRD and EDX analyses. Moreover, the pristine clay was organically modified with hexadecyl trimethyl ammonium chloride before incorporating into PVA-HES membranes. The modification of clay was also verified by FTIR, SEM and XRD analyses. Meanwhile, PVA-hydroxyethyl starch (PVA-HES/modified attapulgite clay) composite hydrogel membranes were fabricated by solution-casting method, where citric acid was utilized as cross-linker for formation of cross-linked membranes. The influence of addition of Egyptian modified attapulgite clay in ratios (0, 1.0, 3.0, 5.0, 7.0 and 10 wt%) on properties of PVA-HES composite membranes was studied in detail. Results revealed that the incorporation of modified attapulgite clay into membranes increased significantly the swelling ability and mechanical stability of composed hydrogel membranes. Also, the increase in clay contents in membranes showed antimicrobial activity against tested six pathogen strains and adequate hemolytic behavior, compared to clay-free membranes. These findings are referring to the capability of using of PVA-HES–attapulgite composite membrane as a good candidate for the purpose of super-absorbent dermal wound dressings.

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Abbreviations

PVA:

Polyvinyl alcohol

HES:

Hydroxyethyl starch

CA:

Citric acid

HDTMA:

Hexadecyl trimethyl ammonium chloride

FTIR:

Fourier-transform infrared spectroscopy

XRD:

X-ray diffraction

SEM:

Scanning electron microscopy

EDX:

Energy-dispersive X-ray spectroscopy

TEM:

Transmission electron microscopy

SWR (%):

Swelling ratio percentage

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Authors and Affiliations

  1. Geology Department, Faculty of Science, Alexandria University, Alexandria, Egypt

    Shrief Elbassyoni, Mohamed A. Rashed & Fathi A. ElNozahi

  2. Polymeric Materials Research Department, Advanced Technology and New Materials Research Institute (ATNMRI), City of Scientific Research and Technological Applications (SRTA-City), New Borg Al-Arab City, 21934, Alexandria, Egypt

    Elbadawy A. Kamoun

  3. Nanotechnology Research Center (NTRC), The British University in Egypt (BUE), El-Sherouk City, 11837, Cairo, Egypt

    Elbadawy A. Kamoun

  4. Environmental Biotechnology Research Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), New Borg Al-Arab City, 21934, Alexandria, Egypt

    Tarek H. Taha

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  1. Shrief Elbassyoni
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  2. Elbadawy A. Kamoun
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Correspondence to Elbadawy A. Kamoun.

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Elbassyoni, S., Kamoun, E.A., Taha, T.H. et al. Effect of Egyptian Attapulgite Clay on the Properties of PVA-HES–Clay Nanocomposite Hydrogel Membranes for Wound Dressing Applications. Arab J Sci Eng 45, 4737–4749 (2020). https://doi.org/10.1007/s13369-020-04501-x

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