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Levels of Aminotransferases Among Schoolchildren in Jaipur, Rajasthan

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Abstract

We did cross-sectional study for normal values of amino-transferases in school children aged 2–18 years. Median (IQR) AST and ALT values in study subjects were 30 (27–34) U/L and 23 (19–29) U/L. We also provided age-and sex-related percentiles of aminotransferases of children. We observed a peak of median AST serum values in the age group 6–8 years followed by continuous decline with increasing age. While in ALT, we observed maximum values in age group 2–5 years followed by continuous decline. There was a statistically significant difference in values of amino-transferases between sexes.

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References

  1. Prati D, Taioli E, Zanella A, et al. Updated definitions of healthy ranges for serum alanine aminotransferase Levels. Ann Intern Med. 2002;137:1–10

    Article  CAS  Google Scholar 

  2. Kariv R, Leshno M, Beth-Or A, et al. Re-evaluation ofserum alanine aminotransferase upper normal limit and its modulating factors in a large-scale population study. Liver Intr. 2006;26: 445–50

    Article  CAS  Google Scholar 

  3. Poustchi H, George J, Esmaili S, et al. Gender differences in healthy ranges for serum alanine aminotransferase levels in adolescence. PLoS One. 2011;6:e21178.

    Article  CAS  Google Scholar 

  4. England K, Thorne C, Pembrey L, Tovo P-A, Newell M-L. Age- and sex-related reference ranges of alanine aminotransferase levels in children: European paediatric HCV network. J Pediatr Gastroenterol Nutr. 2009;49:71–7.

    Article  CAS  Google Scholar 

  5. Dehghani SM, Erjaee A, Haghighat M, Imanieh MH, Ahmadi R. Upper limits of normal aminotransferases in children in Southern Iran. J Compr Ped. 2014;5:15274.

    Article  Google Scholar 

  6. Zierk J, Arzideh F, Rechenauer T, et al. Age- and sexspecific dynamics in 22 hematologic and biochemical analyses from birth to adolescence. Clin Chem. 2015;61:964–73.

    Article  CAS  Google Scholar 

  7. Bussler S, Vogel M, Pietzner D, et al. New pediatric percentiles of liver enzyme serum levels (alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase): Effect of age, sex, body mass index and pubertal stage. Hepatology. 2018;68:1319–30.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Gastroenterology, SMS Medical College and Hospital, Jaipur, Rajasthan, India

    Sandeep Ratra, Kapil Dhingra, Gaurav Kumar Gupta & Sandeep Nijhawan

  2. Department of Health and Family Welfare Department, Kapurthala, Punjab, India

    Sahil Sharma

Authors
  1. Sandeep Ratra
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  2. Kapil Dhingra
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  3. Sahil Sharma
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  4. Gaurav Kumar Gupta
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  5. Sandeep Nijhawan
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Corresponding author

Correspondence to Gaurav Kumar Gupta.

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Contributors

SN, GKG: Concept and designed the study; SR, SS, GKG: Analyzed data and drafted the manuscript; SR, KD: Collected the data and helped in data analysis.

Ethics clearance

IEC, SMS medical college; No 64IMC/RC/2019, dated November 15, 2019.

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None

Competing interests

None stated.

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Ratra, S., Dhingra, K., Sharma, S. et al. Levels of Aminotransferases Among Schoolchildren in Jaipur, Rajasthan. Indian Pediatr 58, 683–684 (2021). https://doi.org/10.1007/s13312-021-2265-8

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  • DOI: https://doi.org/10.1007/s13312-021-2265-8

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