Skip to main content
SpringerLink
Log in

Prevalence of Congenital Heart Disease Amongst Schoolchildren in Southwest China

  • Research Paper
  • Published:
Indian Pediatrics Aims and scope Submit manuscript

Abstract

Objective

To investigate the prevalence and risk factors of congenital heart disease in Yunnan, China which has diverse ethnic groups.

Methods

This cross-sectional study enrolled 244,023 children from 2010 to 2015. To diagnose CHD, a conventional physical examination was used to screen suspicious cases, which were further confirmed by echocardiography.

Results

A total of 1695 children were diagnosed with CHD. The estimated prevalence was 6.94%. Atrial septal defects were the most common cardiac abnormalities. A higher prevalence of CHD was observed with preterm birth, low birth weight, maternal age ≥35 years, and high-altitude regions. The prevalence also showed differences between diverse ethnic groups.

Conclusion

The prevalence of CHD in China may have ethnic differences.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ottaviani, G. and L.M. Buja. Update on congenital heart disease and sudden infant/perinatal death: from history to future trends. J Clin Pathol. 2017;70:555–62.

    Article  Google Scholar 

  2. Hinton RB. Genetic and environmental factors contributing to cardiovascular malformation: A unified approach to risk. J Am Heart Assoc. 2013;2:e000292.

    Article  Google Scholar 

  3. Yu M, Ping Z, Zhang S, He Y, Dong R, Guo X. The survey of birth defects rate based on birth registration system. Chin Med J. 2015;128:7–14.

    Article  Google Scholar 

  4. Yu Z, Xi Y, Ding W, Han S, Cao L, Zhu C, et al. Congenital heart disease in a Chinese hospital: Pre- and postnatal detection, incidence, clinical characteristics and outcomes. Pediatr Int. 2011;53:1059–65.

    Article  Google Scholar 

  5. Liu X, Liu G, Wang P, Huang Y, Liu E, Li D, et al. Prevalence of congenital heart disease and its related risk indicators among 90,796 Chinese infants aged less than 6 months in Tianjin. Int J Epidemiol. 2015;44:884–93.

    Article  Google Scholar 

  6. Zhao QM, Ma XJ, Jia B, Huang GY. Prevalence of congenital heart disease at live birth: An accurate assessment by echocardiographic screening. Acta Paediatr. 2013;102:397–402.

    Article  Google Scholar 

  7. Bjornard K, Riehle-Colarusso T, Gilboa SM, Correa A. Patterns in the prevalence of congenital heart defects, metropolitan Atlanta, 1978 to 2005. Birth Defects Res A Clin Mol Teratol, 2013;97:87–94.

    Article  CAS  Google Scholar 

  8. Sadowski SL. Congenital cardiac disease in the newborn infant: past, present, and future. Crit Care Nurs Clin North Am. 2009;21:37–48, vi.

    Article  Google Scholar 

  9. Miao CY, Zuberbuhler JS, Zuberbuhler JR. Prevalence of congenital cardiac anomalies at high altitude. J Am Coll Cardiol, 1988;12:224–8.

    Article  CAS  Google Scholar 

  10. Chun H, Yue Y, Wang Y, Dawa Z, Zhen P, La Q, et al. High prevalence of congenital heart disease at high altitudes in Tibet. Eur J Prev Cardiol. 2018:. 2047487318812502.

  11. Bishop T, Ratcliffe PJ. HIF hydroxylase pathways in cardiovascular physiology and medicine. Circ Res. 2015;117:65–79.

    Article  CAS  Google Scholar 

  12. Miller A, Riehle-Colarusso T, Siffel C, Frias JL, Correa A. Maternal age and prevalence of isolated congenital heart defects in an urban area of the United States. Am J Med Genet A. 2011;155A:2137–45.

    Article  Google Scholar 

  13. Lopes S, Guimaraes ICB, Costa SFO, Acosta AX, Sandes KA, Mendes CMC. Mortality for critical congenital heart diseases and associated risk factors in newborns. A Cohort Study. Arq Bras Cardiol. 2018;111:666–73.

    PubMed  Google Scholar 

  14. Liu F, Yang YN, Xie X, Li XM, Ma X, Fu, ZY, et al. Prevalence of congenital heart disease in xinjiang multiethnic region of China. PLoS One. 2015;10:e0133961.

    Article  Google Scholar 

  15. Chen QH, Liu FY, Wang XQ, Qi GR, Liu PF, Jin XH, et al. [A cross-sectional study of congenital heart disease among children aged from 4 to 18 years at different altitudes in Qinghai province, China]. Zhonghua Liu Xing Bing Xue Za Zhi. 2009;30:1248–51.

    PubMed  Google Scholar 

Download references

Funding

The National Natural Science Foundation of China (31160230 and 81560060)

Author information

Authors and Affiliations

  1. Department of Cardiovascular Surgery, Yan’an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

    Shen Han, Ya-xiong Li, Dong Huang, Zhu-hui Na & Wen-min Chen

  2. Department of Key Laboratory of Cardiovascular Disease of Yunnan Province, Kunming, Yunnan, China

    Shen Han, Ya-xiong Li, Yun-chuan Ding, Xue-feng Guang, Zhu-hui Na & Wen-min Chen

  3. Department of Central Laboratory, Yan’an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

    Chuan-yu Wei & Zong-liu Hou

  4. Department of Ultrasound, Yan’an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

    Yun-chuan Ding

  5. Department of Cardiology, Yan’an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China

    Xue-feng Guang

  6. Department of First People’s Hospital of Yunnan Province, 157, Jinbi Road, Kunming, Yunnan, 650000, China

    Li-hong Jiang

Authors
  1. Shen Han
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chuan-yu Wei
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zong-liu Hou
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Ya-xiong Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yun-chuan Ding
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Xue-feng Guang
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Dong Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Zhu-hui Na
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Wen-min Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Li-hong Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

SH: drafting the work and revising it critically; CW: agreement to be accountable for all aspects; ZH: design of the work; YL: acquisition of data; YD: acquisition of data; XG: acquisition of data; DH: analysis of data; ZhN: analysis of data; WC: interpretation of data. LJ: final approval of the version to be published. All authors approved the final version of manuscript, and are accountable for all aspects related to the study.

Corresponding author

Correspondence to Li-hong Jiang.

Additional information

Competing interest

None stated.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Han, S., Wei, Cy., Hou, Zl. et al. Prevalence of Congenital Heart Disease Amongst Schoolchildren in Southwest China. Indian Pediatr 57, 138–141 (2020). https://doi.org/10.1007/s13312-020-1731-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13312-020-1731-z

Keywords

Search

Navigation