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Burden of rotavirus diarrhea in under-five Indian children

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Abstract

Need and purpose

Rotavirus is the most common cause of severe diarrhea in infants and young children worldwide. The burden of rotavirus diarrhea in Indian children is not well established. The present study reviewed the epidemiology of rotavirus diarrhea in hospitalized children and in the community, molecular serotyping and under-five mortality caused by rotavirus diarrhea.

Methods

Publications, reporting rotavirus diarrhea in Indian children, were retrieved through a systematic search of databases including Medline, PubMed, IndMed, websites of WHO, UNICEF, National Family Health Survey, Ministry of Health and Family Welfare, and Government of India. ‘Human’ studies in ‘English’ language were included. Age group selected was 0 month to 5 years. No restrictions were applied in terms of study design and time frame.

Conclusions

Stool sample positivity varied from 4.6% in Kolkata to 89.8% in Manipur, among hospitalized children, and from 4% in Delhi to 33.7% in Manipur in community. Most cases of rotavirus diarrhea in India are caused by G1, G2, and G untypeable strains with distinct regional variations. Rotavirus was identified as an etiological agent in 5.2 to 80.5% cases of nosocomial diarrhea. Data are lacking for rotavirus mortality.

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Authors and Affiliations

  1. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Ashok Kumar & Sriparna Basu

  2. Indian Academy of Pediatrics, Kailash Darshan, Kennedy Bridge, Mumbai, India

    Vipin Vashishtha & Panna Choudhury

  3. Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India

    Ashok Kumar

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  1. Ashok Kumar
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  2. Sriparna Basu
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  3. Vipin Vashishtha
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  4. Panna Choudhury
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Correspondence to Ashok Kumar.

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Kumar, A., Basu, S., Vashishtha, V. et al. Burden of rotavirus diarrhea in under-five Indian children. Indian Pediatr 53, 607–617 (2016). https://doi.org/10.1007/s13312-016-0896-y

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