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Association between metabolic control and lipid parameters in Indian children with type 1 diabetes

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Abstract

Objectives

To compare lipid parameters between diabetics and controls and to study association between metabolic control and lipid profile.

Methods

Lipid profile and HbA1c were measured (n=80, 39 boys) in diabetic children [age 10.7(3.4) y] and 54 controls, tests repeated after 1 year (in 45 diabetics).

Results

Diabetic children had higher mean (SD) LDL-C [95.3(27.7) vs 84.5(26.4) mg/dL], lower HDL-C [48.2 (13.1) vs 53.1(11.9) mg/dl]. Moderate physical activity (P=0.014) protected against high LDL-C levels. HbA1c (P=0.00) predicted total and LDL-C levels. At 1year, 63% showed reduced LDL-C with improving HbA1c; 72% showed increased LDL-C with deteriorated HbA1c.

Conclusion

Improving metabolic control is cardinal to reduce cardiometabolic risk; physical activity is beneficial.

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Authors and Affiliations

  1. Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, 411 001, India

    Lavanya Parthasarathy, Shashi Chiplonkar, Vaman Khadilkar & Anuradha Khadilkar

Authors
  1. Lavanya Parthasarathy
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  2. Shashi Chiplonkar
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  3. Vaman Khadilkar
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  4. Anuradha Khadilkar
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Correspondence to Anuradha Khadilkar.

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Parthasarathy, L., Chiplonkar, S., Khadilkar, V. et al. Association between metabolic control and lipid parameters in Indian children with type 1 diabetes. Indian Pediatr 53, 39–41 (2016). https://doi.org/10.1007/s13312-016-0787-2

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  • DOI: https://doi.org/10.1007/s13312-016-0787-2

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