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Growth of very low birth-weight Indian infants during hospital stay

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Abstract

Objectives

To evaluate the growth pattern of Very Low Birth Weight (VLBW) infants (birthweight <1500g) during hospital stay and to compare the growth of Small for gestational age (SGA) and Appropriate for gestational age (AGA) infants.

Study design

Prospective observational study.

Setting

Level III Neonatal Intensive Care Unit (NICU) in Northern India.

Participants

A cohort of 97 VLBW infants, admitted to NICU at Sir Ganga Ram Hospital, from 1 January, 2007 to 31 July, 2008.

Intervention/Measurement

Weight, length and head circumference (HC) were serially measured from birth till discharge and respective Z scores were calculated as per data from Fenton’s references. Growth was also assessed by superimposing these trends on Ehrenkranz’s postnatal growth charts.

Results

The mean Z scores for weight, length and HC at birth were −1.17, −1.09 and −0.54, respectively. These decreased to −2.16, −2.24 and −1.35, respectively by discharge. Both SGA and AGA infants exhibited a decrease of approximately 1 Z score in all parameters. On postnatal charts, growth of infants remained at or above respective reference lines, except in those below 1000g at birth. Average daily weight gain after regaining birth weight was 15.18 ± 1.7 g/kg/d, whereas the increase in HC and length were 0.48 ± 0.2 cm/week and 0.60 ± 0.4 cm/week, respectively. These increments when compared to the intrauterine growth rates, indicated discrepant growth trends.

Conclusions

VLBW infants suffered significant growth lag during NICU stay and exhibited disproportionately slow growth of HC and length.

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References

  1. Hack M, Schluchter M, Cartar L, Rahman M, Cuttler L, Borawski E. Growth of very low birth weight infants to age 20 years. Pediatrics 2003; 112: 30–38.

    Article  Google Scholar 

  2. Astbury J, Orgill AA, Bajuk B, Yu VYH. Sequelae of growth failure in appropriate for gestational age, very low birth weight infants. Dev Med Child Neurol 1986; 28: 472–479.

    Article  CAS  PubMed  Google Scholar 

  3. Lundgren EM, Cnattingius S, Jonsson B, Tuvemo T. Intellectual and psychological performance in males born small for gestational age with or without catch-up growth. Pediatr Res 2001; 50: 91–96.

    Article  CAS  PubMed  Google Scholar 

  4. Hajnal BL, Siebenthal KV, Kovari H, Bucher HU, Largo RH. Postnatal growth in VLBW infants: Significant association with neurodevelopmental outcome. J Pediatr 2003; 143: 163–170.

    Google Scholar 

  5. Fenton TR. A new growth chart for preterm babies: Babson and Benda’s chart updated with recent data and a new format. BMC Pediatr 2003; 3: 13–22.

    Article  PubMed  Google Scholar 

  6. Fenton TR. Preterm Growth Chart 2003 calculations. Available from http://members.shaw.ca/growthchart/FentonGrowthChartcalculations.xls. Accessed on 10 February, 2009.

  7. Ehrenkranz RA, Younes N, Lemons JA, Fanaroff AA, Donovan EF, Wright LL. Longitudinal growth of hospitalized very low birth weight infants. Pediatrics 1999; 104: 280–289.

    Article  CAS  PubMed  Google Scholar 

  8. American Academy of Pediatrics, Committee on Nutritional Needs of Low-Birth-Weight Infants. Pediatrics 1977; 60: 519–530.

    Google Scholar 

  9. American Academy of Pediatrics, Committee on Nutritional Needs of Low-Birth-Weight Infants. Pediatrics 1985; 75: 976–986.

    Google Scholar 

  10. Gutbrod T, Wolke D, Soehne B, Ohrt B, Riegel K. Effects of gestation and birth weight on the growth and development of VLBW small for gestational age infants: A matched group comparision. Arch Dis Child Fetal Neonatal Ed 2000; 82: F 208–214.

    Article  CAS  Google Scholar 

  11. Bertino E, Coscia A, Boni L, Rossi C, Martano C, Giuliani F, et al. Weight growth velocity of very low birth weight infants: role of gender, gestational age and major morbidities. Early Hum Dev 2009; 85: 339–347.

    Article  PubMed  Google Scholar 

  12. Radmacher PG, Looney SW, Rafail ST, Adamkin DH. Prediction of extrauterine growth retardation (EUGR) in VVLBWI. J Perinatol 2003; 23: 392–395.

    Article  PubMed  Google Scholar 

  13. Powls A, Botting N, Cooke RWI, Pilling D, Marlow N. Growth impairment in very low birthweight children at 12 years: correlation with perinatal and outcome variables. Arch Dis Child 1996; 75: F152–F157.

    CAS  Google Scholar 

  14. Hack M, Breslau N, Weissman B, Aram D, Klein N, Borawski E. Effect of very low birth weight and subnormal head size on cognitive abilities at school age. N Engl J Med 1991; 325: 231–237.

    Article  CAS  PubMed  Google Scholar 

  15. Knops NBB, Sneeuw CAK, Brand R, Hille ETM, Ouden AL, Wit JM, et al. Catch-up growth up to ten years of age in children born very preterm or with very low birth weight. BMC Pediatr 2005; 5: 26–34.

    Article  PubMed  Google Scholar 

  16. Yajnik CS, Fall CHD, Coyaji KJ, Hirve SS, Rao S, Barker DJP, et al. Neonatal anthropometry: the thin-fat indian baby. The Pune Maternal Nutrition Study. Int J Obes 2003; 27: 173–180.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Neonatology, Centre for Child Health, Sir Ganga Ram Hospital, New Delhi, India

    Satish Saluja, Manoj Modi, Avneet Kaur, Anil Batra, Arun Soni, Pankaj Garg & Neelam Kler

  2. Department of Neonatology, Sir Ganga Ram Hospital, New Delhi, 110 060, India

    Satish Saluja

Authors
  1. Satish Saluja
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  2. Manoj Modi
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  3. Avneet Kaur
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  4. Anil Batra
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  5. Arun Soni
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  6. Pankaj Garg
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  7. Neelam Kler
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Correspondence to Satish Saluja.

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Saluja, S., Modi, M., Kaur, A. et al. Growth of very low birth-weight Indian infants during hospital stay. Indian Pediatr 47, 851–856 (2010). https://doi.org/10.1007/s13312-010-0146-7

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  • DOI: https://doi.org/10.1007/s13312-010-0146-7

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