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Transoral versus gasless transaxillary endoscopic thyroidectomy: a comparative study

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Abstract

This study aimed to compare the surgical safety and outcomes of the transoral endoscopic thyroidectomy vestibular approach (TOETVA) and gasless endoscopic thyroidectomy transaxillary approach (GETTA). This retrospective study assessed 150 patients managed with the TOETVA at the Yantai Yuhuangding hospital and 150 patients managed via the GETTA at the Zhenjiang Provincial People’s Hospital. The procedures were compared in terms of workspace creation time, operating time, complications, post-operative complaints, cosmetic satisfaction, and the efficacy of central neck lymph-node dissection. There was no significant between-group difference in terms of post-operative complications. The average workspace creation and operating times were significantly shorter for GETTA than for TOETVA (P values for both < 0.001). The average number of lymph nodes dissected from the central compartment of the neck was higher in the TOETVA group than in the GETTA group (7.2 ± 4.6 vs. 3.9 ± 3.0, P < 0.001). The mean swallowing impairment index-6 scores at 1 month were significantly lower in the GETTA group than in the TOETVA group (1.5 ± 1.2 vs 2.6 ± 1.4, P < 0.001). Over 97% of all patients (both groups) were either satisfied or very satisfied with the cervical cosmetic outcomes at 3 months post-surgery (P = 0.099). TOETVA and GETTA are both safe procedures with good cervical cosmetic outcomes for well-selected patients. Although TOETVA is more efficacious in terms of central lymph nodes dissection, GETTA has a greater time–cost advantage.

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Data availability

The datasets generated during and/or analysed during the current study are available from the corresponding author on reasonable request.

References

  1. Wang C, Zhai H, Liu W, Li J, Yang J, Hu Y, Huang J, Yang W, Pan Y, Ding H (2014) Thyroidectomy: a novel endoscopic oral vestibular approach. Surgery 155:33–38

    Article  Google Scholar 

  2. Anuwong A, Sasanakietkul T, Jitpratoom P, Ketwong K, Kim HY, Dionigi G, Richmon JD (2018) Transoral endoscopic thyroidectomy vestibular approach (TOETVA): indications, techniques and results. Surg Endosc 32:456–465

    Article  Google Scholar 

  3. Witzel K, Messenbaeck F, Weitzendorfer M, Benhidjeb T (2017) Transoral thyroidectomy: limitations, patients’ safety, and own experiences. Updates Surg 69:193–198

    Article  Google Scholar 

  4. Dionigi G, Bacuzzi A, Lavazza M, Inversini D, Boni L, Rausei S, Kim HY, Anuwong A (2017) Transoral endoscopic thyroidectomy: preliminary experience in Italy. Updates Surg 69:225–234

    Article  Google Scholar 

  5. Zhang D, Park D, Sun H, Anuwong A, Tufano R, Kim HY, Dionigi G (2019) Indications, benefits and risks of transoral thyroidectomy. Best Pract Res Clin Endocrinol Metab 33:101280

    Article  Google Scholar 

  6. Inabnet WB 3rd, Fernandez-Ranvier G, Suh H (2018) Transoral endoscopic thyroidectomy-an emerging remote access technique for thyroid excision. JAMA Surg 153:376–377

    Article  Google Scholar 

  7. Yoon JH, Park CH, Chung WY (2006) Gasless endoscopic thyroidectomy via an axillary approach: experience of 30 cases. Surg Laparosc Endosc Percutaneous Tech 16:226–231

    Article  Google Scholar 

  8. Zheng CM, Mao XC, Wang JF (2018) Preliminary evaluation of effect of endoscopic thyroidectomy using the gasless unilat-eral axillary approach. Chin J Clin Oncol. https://doi.org/10.3969/j.issn.1000-8179.2018.3901.3801

    Article  Google Scholar 

  9. Yang J, Wang C, Li J, Yang W, Cao G, Wong HM, Zhai H, Liu W (2015) Complete endoscopic thyroidectomy via oral vestibular approach versus areola approach for treatment of thyroid diseases. J Laparoendosc Adv Surg Tech A 25:470–476

    Article  Google Scholar 

  10. Sun H, Zheng H, Wang X, Zeng Q, Wang P, Wang Y (2020) Comparison of transoral endoscopic thyroidectomy vestibular approach, total endoscopic thyroidectomy via areola approach, and conventional open thyroidectomy: a retrospective analysis of safety, trauma, and feasibility of central neck dissection in the treatment of papillary thyroid carcinoma. Surg Endosc 34:268–274

    Article  Google Scholar 

  11. Russell JO, Razavi CR, Al Khadem MG, Lopez M, Saraf S, Prescott JD, Starmer HM, Richmon JD, Tufano RP (2018) Anterior cervical incision-sparing thyroidectomy: comparing retroauricular and transoral approaches. Laryngosc Investig Otolaryngol 3:409–414

    Article  Google Scholar 

  12. Zheng CM, Xu JJ, Jiang LH, Ge MH (2019) Endoscopic thyroid lobectomy by a gasless unilateral axillary approach: Ge & Zheng’s seven-step method. Chin J Gen Surg 28:1336–1341

    Google Scholar 

  13. Kasemsiri P, Trakulkajornsak S, Bamroong P, Mahawerawat K, Piromchai P, Ratanaanekchai T (2020) Comparison of quality of life between patients undergoing transoral endoscopic thyroid surgery and conventional open surgery. BMC Surg 20:18

    Article  Google Scholar 

  14. Russell JO, Clark J, Noureldine SI, Anuwong A, Al Khadem MG, Yub Kim H, Dhillon VK, Dionigi G, Tufano RP, Richmon JD (2017) Transoral thyroidectomy and parathyroidectomy - a North American series of robotic and endoscopic transoral approaches to the central neck. Oral Oncol 71:75–80

    Article  Google Scholar 

  15. Tae K, Lee DW, Song CM, Ji YB, Park JH, Kim DS, Tufano RP (2019) Early experience of transoral thyroidectomy: comparison of robotic and endoscopic procedures. Head Neck 41:730–738

    Article  Google Scholar 

  16. Kim HK, Chai YJ, Dionigi G, Berber E, Tufano RP, Kim HY (2019) Transoral robotic thyroidectomy for papillary thyroid carcinoma: perioperative outcomes of 100 consecutive patients. World J Surg 43:1038–1046

    Article  Google Scholar 

  17. Ahn JH, Yi JW (2020) Transoral endoscopic thyroidectomy for thyroid carcinoma: outcomes and surgical completeness in 150 single-surgeon cases. Surg Endosc 34:861–867

    Article  Google Scholar 

  18. Wang T, Wu Y, Xie Q, Yan H, Zhou X, Yu X, Chen Y, Xiang C, Yan H, Zhao Q, Zhang M, Qi M, Wang P, Wang Y (2020) Safety of central compartment neck dissection for transoral endoscopic thyroid surgery in papillary thyroid carcinoma. Jpn J Clin Oncol 50:387–391

    Article  Google Scholar 

  19. Peng X, Li Z, Li H, Peng W, Zhou X, Song D, Zhou B, Lv C (2020) The clinical application of mental nerve dissection in transoral endoscopic thyroidectomy via an oral vestibular approach. Surg Endosc 34:153–158

    Article  Google Scholar 

  20. Anuwong A, Ketwong K, Jitpratoom P, Sasanakietkul T, Duh QY (2018) Safety and outcomes of the transoral endoscopic thyroidectomy vestibular approach. JAMA Surg 153:21–27

    Article  Google Scholar 

  21. Kim SY, Kim SM, Makay Ö, Chang H, Kim BW, Lee YS, Park CS, Chang HS (2020) Transoral endoscopic thyroidectomy using the vestibular approach with an endoscopic retractor in thyroid cancer: experience with the first 132 patients. Surg Endosc 34:5414–5420

    Article  Google Scholar 

  22. Yi JW, Yoon SG, Kim HS (2018) Transoral endoscopic surgery for papillary thyroid carcinoma: initial experiences of a single surgeon in South Korea. Ann Surg Treat Res 95:73–79

    Article  Google Scholar 

  23. Shin JE, Baek JH, Ha EJ, Choi YJ, Choi WJ, Lee JH (2015) Ultrasound features of middle cervical sympathetic ganglion. Clin J Pain 31:909–913

    Article  Google Scholar 

  24. Saylam CY, Ozgiray E, Orhan M, Cagli S, Zileli M et al (2009) Neuroanatomy of cervical sympathetic trunk: a cadaveric study. Clin Anat 22:324–330

    Article  Google Scholar 

  25. Kim HY, Chai YJ, Dionigi G, Anuwong A, Richmon JD (2018) Transoral robotic thyroidectomy: lessons learned from an initial consecutive series of 24 patients. Surg Endosc 32:688–694

    Article  Google Scholar 

  26. Zheng G, Ma C, Sun H, Wu G, Guo Y, Wu G, Zheng H (2021) Safety and surgical outcomes of transoral endoscopic thyroidectomy vestibular approach for papillary thyroid cancer: a two-centre study. Eur J Surg Oncol. https://doi.org/10.1016/j.ejso.2021.01.028 (Epub ahead of print)

    Article  PubMed  Google Scholar 

  27. Nakajo A, Arima H, Hirata M, Mizoguchi T, Kijima Y, Mori S, Ishigami S, Ueno S, Yoshinaka H, Natsugoe S (2013) Transoral Video-Assisted Neck Surgery (TOVANS). A new transoral technique of endoscopic thyroidectomy with gasless premandible approach. Surg Endosc 27:1105–1110

    Article  Google Scholar 

  28. Hyun K, Byon W, Park HJ, Park Y, Park C, Yun JS (2014) Comparison of swallowing disorder following gasless transaxillary endoscopic thyroidectomy versus conventional open thyroidectomy. Surg Endosc 28:1914–1920

    Article  Google Scholar 

  29. Han S, Kwon TK, Chai YJ, Park J, Lee DY, Lee KE, Kim HY, Hwang KT, Yi KH (2020) Functional voice and swallowing outcome analysis after thyroid lobectomy: transoral endoscopic vestibular versus open approach. World J Surg 44:4127–4135

    Article  Google Scholar 

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Acknowledgements

We would like to thank Editage (http://www.editage.cn) for English language editing.

Funding

The authors received no specific funding for this work.

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Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by GZ, JX, CM, GW, and HS. The first draft of the manuscript was written by GZ and JX. All authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Haitao Zheng or Chuanming Zheng.

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Conflict of interest

The authors have no financial or proprietary interests in any material discussed in this article.

Ethical approval

The authors declare under their responsibility that all the procedures followed in this study were in accordance with the ethical standards issued by the national health and family planning commission and with the Helsinki Declaration. The ethics committee of the affiliated Yantai Yuhuangding Hospital of Qingdao University approved this study (Approval No.: 2020-269).

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Informed consent were obtained from all patients involved in this study.

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Zheng, G., Xu, J., Wu, G. et al. Transoral versus gasless transaxillary endoscopic thyroidectomy: a comparative study. Updates Surg 74, 295–302 (2022). https://doi.org/10.1007/s13304-021-01062-y

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  • DOI: https://doi.org/10.1007/s13304-021-01062-y

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