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New procedures for the identification of sentinel lymph node: shaping the horizon of future management in early stage uterine cervical cancer

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Abstract

Lymph node metastasis is one of the most important prognostic factors for uterine cervical cancer, although lymph node status is not part of the International Federation of Gynaecology and Obstetrics (FIGO) staging. Considering the increasing attention about the topic, we performed a comprehensive review of the literature, to assess the accuracy of real-time fluorescence sentinel lymph node (SLN) for the detection of nodal metastases in patients with early stage cervical cancer (ESCC). In this work, we discuss the different techniques for SLN mapping and the accuracy of each one of them and, basing on these data, summarize the most important recommendations. In particular, we suggest to perform indocyanine green-SLN technique for ESCC, since it showed the highest accuracy for the detection of nodal metastases.

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Authors and Affiliations

  1. Department of Maternal and Child Health, Gavardo Hospital, Brescia, Italy

    Diego Rossetti

  2. Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood ‘‘G. Barresi’’, University of Messina, Via C. Valeria 1, 98125, Messina, Italy

    Salvatore Giovanni Vitale & Antonio Simone Laganà

  3. Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy

    Alessandro Tropea & Antonio Biondi

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  1. Diego Rossetti
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  2. Salvatore Giovanni Vitale
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  4. Antonio Biondi
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  5. Antonio Simone Laganà
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Correspondence to Antonio Simone Laganà.

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Rossetti, D., Vitale, S.G., Tropea, A. et al. New procedures for the identification of sentinel lymph node: shaping the horizon of future management in early stage uterine cervical cancer. Updates Surg 69, 383–388 (2017). https://doi.org/10.1007/s13304-017-0456-6

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