Skip to main content

Advertisement

Log in

Laparoscopic intersphincteric resection: indications and results

  • Original Article
  • Published:
Updates in Surgery Aims and scope Submit manuscript

Abstract

Surgical treatment of distal rectal cancer has long been based only on abdominoperineal excision, resulting in a permanent stoma and not always offering a definitive local control. Sphincter saving surgery has emerged in the last 20 years and can be offered also to patients with low lying tumours, provided that the external sphincter is not involved by the disease. An intersphincteric resection (ISR) is based on the resection of the rectum with a distal dissection proceeding into the space between the internal and the external anal sphincter. Originally described as an open procedure, it has also been developed with the laparoscopic approach, and also this technically demanding procedure is inscribed among those offered to the patient by a minimally invasive surgery. Indications have to be strict and patient selection is crucial to obtain both oncological and functional optimal results. The level of distal dissection and the extent of internal sphincter resected are chosen according to the distal margin of the tumour and is based on MRI findings: accurate imaging is therefore mandatory to better define the surgical approach. We here present our actual indications for ISR, results in terms of operative time, median hospital stay for ISR in our experience and review the updated literature.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Miles WE (1908) A method of performing abdomino perineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon. Lancet 2:1812–1813

    Article  Google Scholar 

  2. Nelson H, Petrelli N, Carlin A et al (2001) Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst 93:583–596

    Article  CAS  PubMed  Google Scholar 

  3. Rullier E, Laurent C, Bretagnol F, Rullier A, Vendrely V, Zerbib F (2005) Sphincter-saving resection for all rectal carcinomas the end of the 2-cm distal rule. Ann Surg 241:3

    Article  Google Scholar 

  4. Guweidhi A, Steffen R, Metzger A, Teuscher J, Flückiger P, Z’graggen K (2009) Circular stapler introducer: a novel device to facilitate stapled colorectal anastomosis. 52(4):746–748. doi:10.1007/DCR.0b013e31819f5e0e. http://www.ncbi.nlm.nih.gov/pubmed/19404085

  5. Sinukumar S, Mehta S, Ostwal V, Jatal S, Saklani A (2015) Impact of type of surgery (laparoscopic versus open) on the time to initiation of adjuvant chemotherapy in operable rectal cancers. Indian J Gastroenterol. 34(4):310–313. doi:10.1007/s12664-015-0579-y (Epub 2015 Aug 7)

    Article  PubMed  Google Scholar 

  6. Rullier E, Sa Cunha A, Couderc P, Rullier A, Gontier R, Saric J (2003) Laparoscopic intersphincteric resection with coloplasty and coloanal anastomosis for mid and low rectal cancer. Br J Surg 90(4):445–451

    Article  CAS  PubMed  Google Scholar 

  7. Watanabe M, Teramoto T, Hasegawa H, Kitajima M (2000) Laparoscopic ultralow anterior resection combined with per anum intersphincteric rectal dissection for lower rectal cancer. Dis Colon Rectum 43(10 Suppl):S94–S97

    Article  CAS  PubMed  Google Scholar 

  8. Schiessel R, Novi G, Holzer B, Rosen HR, Renner K, Hölbling N, Feil W, Urban M (2005) Technique and long-term results of intersphincteric resection for low rectal cancer. Dis Colon Rectum 48(10):1858–1865 (discussion 1865–7)

    Article  PubMed  Google Scholar 

  9. Shirouzu K, Ogata Y (2009) Histopathologic tumor spread in very low rectal cancer treated with abdominoperineal resection. Dis Colon Rectum 52(11):1887–1894. doi:10.1007/DCR.0b013e3181b1585a

    Article  PubMed  Google Scholar 

  10. Chi P, Huang SH, Lin HM, Lu XR, Huang Y, Jiang WZ, Xu XB, Chen ZF, Sun YW, Ye DX (2015) Laparoscopic transabdominal approach partial intersphincteric resection for low rectal cancer: surgical feasibility and intermediate-term outcome. Ann Surg Oncol 22:944–951. doi:10.1245/s10434-014-4085-8

    Article  PubMed  Google Scholar 

  11. Birbeck KF, Macklin CP, Tiffin NJ et al (2002) Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery. Ann Surg 235:449–457

    Article  PubMed  PubMed Central  Google Scholar 

  12. Scheele J, Lemke J, Meier M, Sander S, Henne-Bruns D, Kornmann M (2015) Quality of life after sphincter-preserving rectal cancer resection. Clin Colorectal Cancer. doi:10.1016/j.clcc.2015.05.012

    PubMed  Google Scholar 

  13. Jayne DG, Guillou PJ, Thorpe H, Quirke P, Copeland J, Smith AMH, Heath RM, Brown JM (2007) Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group. J Clin Oncol 25:3061–3068

    Article  PubMed  Google Scholar 

  14. Green BL, Marshall HC, Collinson F, Quirke P, Guillou P, Jayne DG, Brown JM (2013) Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer. Br J Surg 100(1):75–82. doi:10.1002/bjs.8945 (Epub 2012 Nov)

    Article  CAS  PubMed  Google Scholar 

  15. Buurma M, Kroon HM, Reimers MS, Neijenhuis PA (2015) Influence of individual surgeon volume on oncological outcome of colorectal cancer surgery. Int J Surg Oncol 2015:464570. doi:10.1155/2015/464570 (Epub 2015 Sep 3)

    PubMed  PubMed Central  Google Scholar 

  16. Liu CJ, Chou YJ, Teng CJ, Lin CC, Lee YT, Hu YW, Yeh CM, Chen TJ, Huang N (2015) Association of surgeon volume and hospital volume with the outcome of patients receiving definitive surgery for colorectal cancer: a nationwide population-based study. Cancer 121(16):2782–2790. doi:10.1002/cncr.29356 (Epub 2015 Apr 17)

    Article  PubMed  Google Scholar 

  17. Masaaki Ito Æ, Masanori Sugito Æ, Akihiro Kobayashi Æ, Yusuke Nishizawa Æ, Yoshiyuki Tsunoda Æ, Saito Norio (2009) Influence of learning curve on short-term results after laparoscopic resection for rectal cancer. Surg Endosc 23:403–408. doi:10.1007/s00464-008-9912-1

    Article  PubMed  Google Scholar 

  18. Kayano H, Okuda J, Tanaka K, Kondo K, Tanigawa N (2011) Evaluation of the learning curve in laparoscopic low anterior resection for rectal cancer. Surg Endosc 25:2972–2979. doi:10.1007/s00464-011-1655-8

    Article  PubMed  Google Scholar 

  19. Lim SW, Huh JW, Kim YJ, Kim HR (2011) Laparoscopic Intersphincteric Resection for Low Rectal Cancer. World J Surg 35:2811–2817. doi:10.1007/s00268-011-1277-2

    Article  PubMed  Google Scholar 

  20. Fujimoto Y, Akiyoshi T, Kuroyanagi H, Konish T, Ueno M, Oya M, Yamaguchi T (2010) Safety and feasibility of laparoscopic intersphincteric resection for very low rectal cancer. J Gastrointest Surg 14:645–650. doi:10.1007/s11605-009-1150-x

    Article  PubMed  Google Scholar 

  21. Motson RW, Lacy A (2015) The rationale for transanal total mesorectal excision. Dis Colon Rectum 58(9):911–913. doi:10.1097/DCR.0000000000000422

    Article  PubMed  Google Scholar 

  22. Nicholson G, Knol J, Houben B, Cunningham C, Ashraf S, Hompes R (2015) Optimal dissection for transanal total mesorectal excision using modified CO2 insufflation and smoke extraction. Colorectal Dis 17(11):O265–O267. doi:10.1111/codi.13074

    Article  CAS  PubMed  Google Scholar 

  23. Pace U, Rega D, Scala D, Montesarchio L, Delrio P (2014) Skin bridge loop ileostomy: technical details. Tech Coloproctol 18(9):855–856. doi:10.1007/s10151-014-1142-z (Epub 2014 Apr 10)

    Article  CAS  PubMed  Google Scholar 

  24. Ueno H, Mochizuki H, Hashiguchi Y, Ishikawa K, Fujimoto H, Shinto E, Hase K (2004) Preoperative parameters expanding the indication of sphincter preserving surgery in patients with advanced low recatal cancer. Ann Surg 239(1):34–42

    Article  PubMed  PubMed Central  Google Scholar 

  25. Shirozu K, Ogata Y (2009) Histopathologic tumor spread in very low rectal cancer trated with abdominoperineal resection. Dis Colon Rectum 52:1887–1984

    Article  Google Scholar 

  26. Schiessel R, Karner-Hanusch J, Herbst F, Teleky B, Wunderlich M (1994) Intersphincteric resection for low rectal tumours. Br J Surg 81(9):1376–1378

    Article  CAS  PubMed  Google Scholar 

  27. Watanabe M, Teramoto T, Hasegawa H, Kitajima M (2000) Laparoscopic ultralow anterior resection combined with per anum intersphincteric rectal dissection for lower rectal cancer. Dis Colon Rectum 43(Suppl):S94–S97

    Article  CAS  PubMed  Google Scholar 

  28. Laurent C, Paumet T, Leblanc F, Denost Q, Rullier E (2010) Intersphincteric resection for low rectal cancer: laparoscopic vs open surgery approach. Colorectal Dis 14:35–43

    Article  Google Scholar 

  29. Martin ST, Heneghan HM, Winter DC (2012) Systematic review of outcomes after intersphincteric resection for low rectal cancer. Br J Cancer 99:603–612

    CAS  Google Scholar 

  30. Park SY, Choi GS, Park JS, Kim HJ, Ryuk JP (2013) Short-term clinical outcome of robot-assisted intersphincteric resection for low rectal cancer: a retrospective comparison with conventional laparoscopy. Surg Endosc 27(1):48–55. doi:10.1007/s00464-012-2405-2 (Epub 2012 Jun 30)

    Article  PubMed  Google Scholar 

  31. Bretagnol F, Rullier E, Couderc P, Rullier A, Saric J (2003) Technical and oncological feasibility of laparoscopic total mesorectal excision with pouch coloanal anastomosis for rectal cancer. Colorectal Dis 5(5):451–453

    Article  CAS  PubMed  Google Scholar 

  32. Karakayali FY, Tezcaner T, Moray G (2015) Specimen extraction from the defunctioning ileostomy site or Pfannenstiel incision during total laparoscopic low anterior resection for rectal cancer. J Laparoendosc Adv Surg Tech A 25(5):380–385. doi:10.1089/lap.2014.0545 (Epub 2015 Mar 13)

    Article  PubMed  Google Scholar 

  33. Wolthuis AM, Fieuws S, Van Den Bosch A, de Buck van Overstraeten A, D’Hoore A (2015) Randomized clinical trial of laparoscopic colectomy with or without natural-orifice specimen extraction. Br J Surg 102(6):630–637. doi:10.1002/bjs.9757 (Epub 2015 Mar 12)

    Article  CAS  PubMed  Google Scholar 

  34. Ho YH, Brown S, Heah SM, Tsang C, Seow-Choen F, Eu KW, Tang CL (2002) Comparison of J-pouch and coloplasty pouch for low rectal cancers: a randomized, controlled trial investigating functional results and comparative anastomotic leak rates. Ann Surg 236(1):49–55

    Article  PubMed  PubMed Central  Google Scholar 

  35. Neutzling CB, Lustosa SA, Proenca IM, da Silva EM, Matos D (2012) Stapled versus handsewn methods for colorectal anastomosis surgery. Cochrane Database Syst Rev 2:CD003144. doi:10.1002/14651858.CD003144.pub2

    PubMed  Google Scholar 

  36. Cong JC, Chen CS, Ma MX, Xia ZX, Liu DS, Zhang FY (2014) Laparoscopic intersphincteric resection for low rectal cancer: comparison of stapled and manual coloanal anastomosis. Colorectal Dis 16(5):353–358. doi:10.1111/codi.12573

    Article  CAS  PubMed  Google Scholar 

  37. Hallet J, Milot H, Drolet S, Desrosiers E, Grégoire RC, Bouchard A (2014) The clinical results of the Turnbull–Cutait delayed coloanal anastomosis: a systematic review. Tech Coloproctol 18(6):579–590. doi:10.1007/s10151-014-1132-1 (Epub 2014 Mar 11)

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Dario Scala.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures in our paper were in accordance with the ethical standards of the institutional as well as national research committee and with the 1964 Helsinki declaration and its later amendments.

Research involving human participants and/or animals

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

For this type of study formal consent is not required.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Scala, D., Niglio, A., Pace, U. et al. Laparoscopic intersphincteric resection: indications and results. Updates Surg 68, 85–91 (2016). https://doi.org/10.1007/s13304-016-0351-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13304-016-0351-6

Keywords

Navigation