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Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation

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Abstract

Rupture properties of thoracic aortic aneurysms (TAAs) were measured in vitro in a pressure-imposed test to predict the ultimate stress of TAAs from their mechanical behavior in a physiological pressure range. Each quadrilateral (ca. 20 × 20 mm2) specimen of TAAs or porcine thoracic aortas (PTAs) was pressurized from the inner wall until rupture or up to 4500 mmHg, while its deformation was being monitored. In-plane stress σ and strain ε of the specimen were calculated using Laplace’s law and deformations of the markers drawn on the specimen surface, respectively. Ultimate stress σ max and tangent elastic modulus H were determined from the σ–ε curve as its maximum stress and slope, respectively. The tangent elastic modulus H of PTA specimens tended to increase with the increase in σ, while that of TAA specimens tended to reach a plateau in a low-σ region. This tendency was confirmed by fitting a function H = C σ (1 − exp(−σ/τ σ )) to the H−σ relation of specimens: The yielding parameter τ σ was significantly lower in TAAs than PTAs. Furthermore, the logarithm of the parameter τ σ correlated significantly with σ max, for all specimens. These results may indicate that τ σ is one of the candidate indices for rupture risk estimation.

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Acknowledgments

The authors thank patients who allowed us to use their aneurysm specimens. The present study was supported in part by Grants-in-Aid for Young Scientists (B) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan (No. 22700467) and the Science and Technology Promotion Adjustment Cost Program from the Japan Science and Technology Agency.

Conflict of interest

The authors have no financial and personal relationships with the other people or organizations that could inappropriately influence our work.

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Authors and Affiliations

  1. Department of Mechatronics and Precision Engineering, Graduate School of Engineering, Tohoku University, 6-6-01 Aramaki Aza Aoba, Aoba-ku, Sendai, 980-8579, Japan

    Shukei Sugita, Takeo Matsumoto, Toshiro Ohashi & Masaaki Sato

  2. Department of Cardiovascular Surgery, Graduate School of Medicine, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan

    Kiichiro Kumagai, Hiroji Akimoto & Koichi Tabayashi

  3. Center for Fostering Young and Innovative Researchers, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan

    Shukei Sugita

  4. Biomechanics Laboratory, Department of Mechanical Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, 466-8555, Japan

    Takeo Matsumoto

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  1. Shukei Sugita
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  2. Takeo Matsumoto
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  3. Toshiro Ohashi
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  4. Kiichiro Kumagai
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  5. Hiroji Akimoto
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  7. Masaaki Sato
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Correspondence to Takeo Matsumoto.

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Associate Editor Tim McGloughlin oversaw the review of this article.

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Sugita, S., Matsumoto, T., Ohashi, T. et al. Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation. Cardiovasc Eng Tech 3, 41–51 (2012). https://doi.org/10.1007/s13239-011-0067-1

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  • DOI: https://doi.org/10.1007/s13239-011-0067-1

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