Abstract
Sodium acrylate (AANa) and hydroxyethyl methacrylate (HEMA) were synthesized by bulk polymerization technique to achieve a pH-responsive, super-absorbent hydrogel (SHG) copolymer. The synthesized copolymer was confirmed by FTIR spectroscopy. The pH responsive behavior of the SHG with different monomer ratios of HEMA and AA was investigated, and the SHG showed significant swelling properties at pH 7. The hydrogels were evaluated for the influences of crosslinking agent content, changes in the surface/cross-sectional morphology according to the degree of crosslinking, the water-absorbing properties of swellable SHG, and the adhesion properties to other polymer surfaces. The SHG hydrogel also exhibited good biocompatibility, low cytotoxicity, and high cell viability. The synthesized SHG hydrogel could be used for wound dressing materials in clinical applications requiring high absorption capacity when body fluids are heavily secreted from a wound site. Poly(AA-co-HEMA) hydrogels (SHG) may also have potential uses in biomedical applications such as wound healing and tissue engineering.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
F.L. Buchhlz and T. Graham, Modern Superabsorbent Polymer Technology, Wiley-VCH, New York, 1998.
T. Sawai, S. Yamazaki, Y. Ishigami, Y. Ikariyama, and M. Aizawa, Macromolecules, 24, 5801 (1991).
A. Pourjavadi, M. S. Amini-Fazl, and H. Hossinzadeh, Macromol. Res., 13, 45 (2005).
T. Gao, W. Wang, and A. Wang, Macromol. Res., 19, 739 (2011).
G. F. Fanta, R. C. Burr, and C. E. Rist, J. Appl. Polym. Sci., 10, 929 (1966).
G. F. Fanta, R. C. Burr, C. R. Russell, and C. E. Rist, J. Appl. Polym. Sci., 11, 457 (1967).
G. F. Fanta, R. C. Burr, and C. E. Rist, J. Polym. Sci. Part B: Polym. Phys., 4, 765 (1966).
V. D. Athawale and L. Vidyagauri, Carbohydr. Polym., 35, 21 (1998).
R. X. Lin, Y. L. Huang, and A. Niu, J. Polym. Mater. Sci. Eng., 15, 118 (1999).
D. T. Tian, J. S. Guo, and L. Q. Xie, J. Appl. Chem., 14, 18 (1997).
G. R. Umbreit and R. L. Houtman, J. Pharm. Sci., 56, 349 (1967).
P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenney, and M. R. Boyd, J. Natl. Cancer. Inst., 82, 1107 (1990).
S. Wen, X. Yin, and W. T. K. Stevenson, J. Appl. Polym. Sci., 42, 1399 (1991).
Y. K. Son, Y. P. Jung, J.-H. Kim, and D. J. Chung, Macromol. Res., 14, 394 (2006).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Shin, B.M., Kim, JH. & Chung, D.J. Synthesis of pH-responsive and adhesive super-absorbent hydrogel through bulk polymerization. Macromol. Res. 21, 582–587 (2013). https://doi.org/10.1007/s13233-013-1051-4
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13233-013-1051-4