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Preparation of Furfuryl-fish gelatin (F-f.gel) cured using visible-light and its application as an anti-adhesion agent

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Abstract

Adhesions occurring on a variety tissues and operation sites are a serious side effect of surgery and may require additional surgery for removal. Therefore, Furfuryl-fish gelatin (F-f.gel) was synthesized by introducing a furan ring to fish gelatin for application as an anti-adhesion agent. F-f.gel was cured by visible-light irradiation, which changed the material from a solution to a film. The prepared F-f.gel was characterized by proton nuclear magnetic resonance spectroscopy (1H NMR), substitution ratio, gel permeation chromatography (GPC), methyl thiazolyl tetrazolium (MTT) assay, and tests for measuring photo immobilization, water contact angle (WCA), and cell attachment. The results showed that F-f.gel was effective as an anti-adhesion agent.

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Authors and Affiliations

  1. Department of Biotechnology and Bio-Environmental Technology (BET) Research Institute, Chung-Ang University, Gyeonggi, 456-756, Korea

    Shin-Hye Park, Si-Yoong Seo, Hyung-Jae Lee, Ha-Na Na, Jea-Woo Lee, Hee-Dong Woo & Tae-Il Son

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  1. Shin-Hye Park
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  2. Si-Yoong Seo
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  3. Hyung-Jae Lee
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  4. Ha-Na Na
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  5. Jea-Woo Lee
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  6. Hee-Dong Woo
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  7. Tae-Il Son
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Correspondence to Tae-Il Son.

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Park, SH., Seo, SY., Lee, HJ. et al. Preparation of Furfuryl-fish gelatin (F-f.gel) cured using visible-light and its application as an anti-adhesion agent. Macromol. Res. 20, 842–846 (2012). https://doi.org/10.1007/s13233-012-0128-9

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  • DOI: https://doi.org/10.1007/s13233-012-0128-9

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