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Biogenic synthesis of iron oxide nanorods using Moringa oleifera leaf extract for antibacterial applications

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Abstract

Biogenic synthesis of iron oxide nanorods (FeO-NRs) from FeCl3 capped with Moringa oleifera (MO) has been developed in this work. The facile, cost effective, and eco-friendly FeO-NRs formulated were characterized using various techniques. The change in the visible color which leads to the formulation of FeO-NRs was confirmed by the UV–visible spectroscopy analysis. The crystallinity of FeO-NRs was observed in the X-ray diffraction spectroscopy pattern indexed to the spinel cubic lattice in the tetrahedral hematite structure. A rod-like morphology of FeO-NRs with the average particle size of 15.01 ± 6.03 nm was determined by the scanning and transmission electron microscopies. Fourier transform infrared spectroscopy analysis shows the various functional groups in the formulatedFeO-NRs. Vibrating sample magnetometer shows that the formulated FeO-NRs are superparamagnetic with good saturation magnetization. The formulated FeO-NRs inhibit the growth of six human pathogens with a higher activity at lower concentrations. It is noteworthy that the bacterial strains show strong and effective susceptibility to the formulated FeO-NRs at lower concentrations compared to the conventional antibacterial drugs. Hence, the formulated FeO-NRs proved to be a good, efficient, and promising antibacterial agent due to its cost-effectiveness, non-toxicity, and facile synthesis procedures in therapeutic biomedical fields.

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Acknowledgements

Samson O. Aisida (NCP-CAAD/TWAS_Fellow8408) acknowledges the NCP-TWAS Postdoc Fellowship award. FIE (90407830) acknowledges UNISA for VRSP Fellowship award; he also acknowledges the grant by TETFUND under contract number TETF/DESS/UNN/NSUKKA/STI/VOL.I/B4.33. Also, we thank Engr. Emeka Okwuosa for the sponsorship of 2014, 2016, and 2018 nano-conferences/workshops.

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Authors and Affiliations

  1. Department of Physics and Astronomy, University of Nigeria, Nsukka, Nigeria

    Samson O. Aisida, Ngozi Madubuonu & Fabian I. Ezema

  2. National Center for Physics, Islamabad, Pakistan

    Samson O. Aisida & Ishaq Ahmad

  3. Department of Physics, COMSATS University, Islamabad, 44000, Pakistan

    M. Hisham Alnasir

  4. NPU-NCP Joint International Research Center on Advanced Nanomaterials and Defects Engineering, Northwestern Polytechnical University, Xi’an, 710072, China

    Ishaq Ahmad

  5. Nanosciences African Network (NANOAFNET), iThemba LABS-National Research, Western Cape, South Africa

    Ishaq Ahmad, M. Maaza & Fabian I. Ezema

  6. UNESCO-UNISA Africa Chair in Nanosciences/Nanotechnology, College of Graduate Studies, University of South Africa (UNISA), Muckleneuk Ridge, P.O. Box 392, Pretoria, South Africa

    Ishaq Ahmad, M. Maaza & Fabian I. Ezema

  7. Microscopy Unit, University of Western Cape, Western Cape, South Africa

    S. Botha

  8. Department of Physics, Faculty of Natural and Applied Sciences, Coal City University, Enugu, Nigeria

    Fabian I. Ezema

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  1. Samson O. Aisida
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Aisida, S.O., Madubuonu, N., Alnasir, M.H. et al. Biogenic synthesis of iron oxide nanorods using Moringa oleifera leaf extract for antibacterial applications. Appl Nanosci 10, 305–315 (2020). https://doi.org/10.1007/s13204-019-01099-x

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