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Molecular Biology of Lung Cancer—A Review

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Indian Journal of Surgical Oncology Aims and scope Submit manuscript

Abstract

Lung cancer is leading site of cancer in Indian males today. The incidence is on the rise. It is generally diagnosed in late stages. The progression free survival and overall survival still remains low. Majority of oncology research today is driven towards molecular profiling of lung cancer. Receptor tyrosine kinases have emerged as major molecular markers and targets. These are the results of gene mutations or amplifications. There are many developed targets where therapeutic option is available like EGFR, ALK, MET, KRAS and so on. This review features on few important molecular profiles of lung cancer, especially with more therapeutic implications.

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Authors and Affiliations

  1. Asian Institute of Oncology, S. L. Raheja Hospital, Mahim, Mumbai, 400016, India

    Dinesh Pendharkar

  2. Shree Siddheshwar Cancer Hospital & Research Center, Sholapur, India

    B. V. Ausekar

  3. Cancer Institute Adiyar, Chennai, India

    Sumant Gupta

Authors
  1. Dinesh Pendharkar
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  2. B. V. Ausekar
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  3. Sumant Gupta
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Correspondence to Dinesh Pendharkar.

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Pendharkar, D., Ausekar, B.V. & Gupta, S. Molecular Biology of Lung Cancer—A Review. Indian J Surg Oncol 4, 120–124 (2013). https://doi.org/10.1007/s13193-013-0213-3

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  • DOI: https://doi.org/10.1007/s13193-013-0213-3

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