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Laser in infra-popliteal and popliteal stenosis (LIPS): retrospective review of laser-assisted balloon angioplasty versus balloon angioplasty alone for below knee peripheral arterial disease

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Abstract

Despite the use of laser technology over the last decade, there are limited data to show its procedural and clinical success in infra-popliteal disease. We hypothesized that laser-assisted balloon angioplasty (LABA) is at least similar or better in procedural and peri-procedural outcomes compared to balloon angioplasty (BA) alone, despite adverse lesion characteristics prior to intervention. Retrospective chart and angiogram review of consecutive critical limb ischemia (CLI) patients who underwent endovascular revascularization in the popliteal or infra-popliteal vessels between 2007 and 2012 with LABA or BA alone. Data from 731 patients revealed that baseline demographics were similar in the LABA (n = 398) and BA group (n = 333) with minor exceptions. More patients in the LABA group had TASC-D lesions (92.5 vs. 66.7 %; P < 0.0001) and chronic total occlusions (CTOs) in both vessel 1 (86.4 vs. 49.5 %; P < 0.0001) and vessel 2 (78.6 vs. 47.8 %; P < 0.0001). Multivariate analysis performed using logistic regression after adjusting for confounding factors showed use of LABA was associated with a 7 times greater likelihood of achieving <50 % residual disease compared to BA alone (OR 7.59, P < 0.0001), and a 5 times greater likelihood of improvement in the infra-popliteal lesion severity score than balloon angioplasty alone (OR 4.77, p < 0.0001). LABA is significantly better at achieving angiographic success and improving lesion severity score in spite of adverse lesion characteristics (more TASC-D lesions and CTOs) compared with BA alone. Our findings suggest that the use of LABA is an endovascular approach that is at least as effective and safe or better compared to BA for the treatment of CLI from complex popliteal and infra-popliteal vascular disease.

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Acknowledgments

Spectranetics Corp funded the study.

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Authors and Affiliations

  1. LIPS study group, St John Hospital and Medical Center, Detroit, MI, USA

    Tejwant Singh, Mihas Kodenchery, Surya Artham, Chatchawan Piyaskulkaew, Susanna Szpunar, Kesav Parvataneni, Hussein Ballout, Haroon Chugtai, Douglas Stewart, Thomas Lalonde & Hiroshi Yamasaki

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  1. Tejwant Singh
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  2. Mihas Kodenchery
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  3. Surya Artham
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  4. Chatchawan Piyaskulkaew
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  6. Kesav Parvataneni
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  7. Hussein Ballout
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Correspondence to Hiroshi Yamasaki.

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Singh, T., Kodenchery, M., Artham, S. et al. Laser in infra-popliteal and popliteal stenosis (LIPS): retrospective review of laser-assisted balloon angioplasty versus balloon angioplasty alone for below knee peripheral arterial disease. Cardiovasc Interv and Ther 29, 109–116 (2014). https://doi.org/10.1007/s12928-013-0217-5

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  • DOI: https://doi.org/10.1007/s12928-013-0217-5

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