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Structural Changes in the Pancreas and Its Blood Vessels at the Early Stages of Ischemia

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Abstract

The rat pancreas structure was studied in the settings of experimental ischemia using the methods of electron microscopy, EPR and NMR spectroscopy. The earliest changes in the pancreatic capillary structure occur in 5 min after ischemia. As the ischemia progresses, there is an increased intensity of signal from iron-sulfur proteins as well as its decrease from an oxidized center of succinate coenzyme reductase, a decreased intensity of that from phosphocreatine and ATP γ-fraction as well as a rising intensity of signal from inorganic phosphate.

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Acknowledgments

This study was supported by the Russian Government Program of Competitive Growth of Kazan Federal University and subsidy allocated to Kazan Federal University for the state assignment in the sphere of scientific activities.

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Authors and Affiliations

  1. Kazan State Medical University, Butlerova str., 49, Kazan, Russia, 420012

    Renat K. Kadirov

  2. Kazan Federal University, Kremlevskaya str., 18, Kazan, Russia, 420000

    Svetlana S. Arkhipova & Albert A. Rizvanov

  3. I.M. Sechenov First Moscow State University, 2-4 Bolshaya Pirogovskaya st., Moscow, Russia, 119991

    Svetlana A. Shahmardanova

Authors
  1. Renat K. Kadirov
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  2. Svetlana S. Arkhipova
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  3. Svetlana A. Shahmardanova
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  4. Albert A. Rizvanov
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Correspondence to Albert A. Rizvanov.

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Kadirov, R.K., Arkhipova, S.S., Shahmardanova, S.A. et al. Structural Changes in the Pancreas and Its Blood Vessels at the Early Stages of Ischemia. BioNanoSci. 6, 293–296 (2016). https://doi.org/10.1007/s12668-016-0265-2

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  • DOI: https://doi.org/10.1007/s12668-016-0265-2

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