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Comparative study of catheter drainage and needle aspiration in management of large liver abscesses

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Abstract

Objective

To compare the effectiveness of percutaneous catheter drainage (PCD) and percutaneous needle aspiration (PNA) in the management of large (>10 cm diameter) liver abscesses.

Methods

Seventy-two patients with liver abscess (amebic 48, pyogenic 24) were randomly allocated to PCD or PNA (36 each), which were done within 24 hours of admission. Both groups received parenteral antibiotics for at least 10 days. PNA was repeated every third day if the cavity size had not declined to 50% of the original for up to three times. Persistence of cavity or of clinical symptoms was considered failure of treatment. Duration to attain clinical relief, duration of hospital stay, complications, treatment failure, and deaths were recorded.

Results

PNA was successful in 31 of 36 (86%) patients (one aspiration in 10, two in 18, and three in 3 patients), whereas PCD was successful in 35 (97%) patients (p=ns). Duration to attain clinical relief (10.2 [2.0] vs. 8.1 [2.7] days; p=0.02) and parenteral antibiotics needed (15.5 [1.1] vs. 10.9 [2.7] days; p=0.04) were significantly lower in PCD group. Duration of hospital stay was similar in the two groups. One patient with PNA had a subcapsular hematoma and one with PCD had continuous bile leakage which stopped spontaneously. One patient in PCD group died.

Conclusion

PCD is a better treatment option than PNA for the management of large liver abscesses of size >10 cm, in terms of duration to attain clinical relief and duration for which parenteral antibiotics are needed.

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References

  1. Sharma MP, Ahuja V. Management of amebic and pyogenic liver abscess. Indian J Gastroenterol 2001;20(Suppl 1):C33–C36.

    PubMed  Google Scholar 

  2. Thompson JE Jr, Forlenza S, Verma R. Amebic liver abscess: a therapeutic approach. Rev Infect Dis 1985;7:171–179.

    Article  PubMed  Google Scholar 

  3. Seeto RK, Rockey DC. Pyogenic liver abscess: changes in etiology, management and outcome. Medicine (Baltimore) 1996;75:99–113.

    Article  CAS  Google Scholar 

  4. Wong KP. Percutaneous drainage of pyogenic liver abscess. World J Surg 1990;14:492–497.

    Article  CAS  PubMed  Google Scholar 

  5. Rajak CL, Gupta S, Jain S, Chawla Y, Gulati M, Suri S. Percutaneous treatment of liver abscesses: needle aspiration versus catheter drainage. Am J Roentgenol 1998;170:1035–1039.

    Article  CAS  Google Scholar 

  6. Yu SC, Ho SS, Lau WY, et al. Treatment of pyogenic liver abscess: prospective randomized comparison of catheter drainage and needle aspiration. Hepatology 2004;39;932–938.

    Article  PubMed  Google Scholar 

  7. Zerem E, Hadzic A. Sonographically guided percutaneous catheter drainage versus needle aspiration in the management of pyogenic liver abscess. Am J Roentgenol 2007;189:W138–W142.

    Article  Google Scholar 

  8. Saraswat VA, Agarwal DK, Baijal SS, et al. Percutaneous catheter drainage of amoebic liver abscesses. Clin Radiol 1992;45:187–189.

    Article  CAS  PubMed  Google Scholar 

  9. VanSonnenberg E, D’Agostino HB, Casola G, Halasz NA, Sanchez RB, Goodacre BW. Percutaneous abscess drainage: current concepts. Radiology 1991;181:617–626.

    CAS  PubMed  Google Scholar 

  10. Lambiase RE, Deyoe L, Cronan JJ, Dorfman GS. Percutaneous drainage of 335 liver abscesses: results of primary drainage with 1 year follow up. Radiology 1992;184:167–179.

    CAS  PubMed  Google Scholar 

  11. Juul N, Sztuk FJ, Torp-Pedersen S, Burcharth F. Ultrasonically guided percutaneous treatment of liver abscesses. Acta Radiol 1990;31:275–279.

    Article  CAS  PubMed  Google Scholar 

  12. Baek SY, Lee MG, Cho KS, Lee SC, Sung KB, Auh YH. Therapeutic percutaneous aspiration of hepatic abscesses: effectiveness in 25 patients. Am J Roentgenol 1993;160:799–802.

    Article  CAS  Google Scholar 

  13. Ch Yu S, Hg Lo R, Kan PS, Metreweli C. Pyogenic liver abscess: treatment with needle aspiration. Clin Radiol 1997;52:912–916.

    Article  CAS  PubMed  Google Scholar 

  14. Giorgio A, Tarantino L, Mariniello N, et al. Pyogenic liver abscesses: 13 years of experience in percutaneous needle aspiration with US guidance. Radiology 1995;195:122–124.

    CAS  PubMed  Google Scholar 

  15. Mohsen AH, Green ST, Read RC, McKendrick MW. Liver abscess in adults: ten years experience in a UK centre. Q J Med 2002;95:797–802.

    Article  CAS  Google Scholar 

  16. Pitt HA. Surgical management of hepatic abscesses. World J Surg 1990;14:141–152.

    Article  Google Scholar 

  17. Wong WM, Wong BC, Hui CK, et al. Pyogenic liver abscess: retrospective analysis of 80 cases over a 10-year period. J Gastroenterol Hepatol 2002;17:1001–1007.

    Article  PubMed  Google Scholar 

  18. Chou FF, Sheen-Chen SM, Chen YS, Chen MC, Chen CL. Single and multiple pyogenic liver abscesses: clinical course, etiology, and results of treatment. World J Surg 1997;21:384–389.

    Article  CAS  PubMed  Google Scholar 

  19. Sherlock S, Dooley Y. Disease of the liver and biliary system. 9th ed. Oxford: Blackwell, 1993:pp. 471–502.

    Google Scholar 

  20. Sharma MP, Rai RR, Acharya SK, Ray JC, Tandon BN. Needle aspiration of amoebic liver abscess. BMJ 1989;299:1308–1309.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  21. Hashimoto L, Hermann R, Grundfest-Broniatowski S. Pyogenic hepatic abscess: results of current management. Am Surg 1995;61:407–411.

    CAS  PubMed  Google Scholar 

  22. Stain SC, Yellin AE, Donovan AJ, Brien HW. Pyogenic liver abscess: modem treatment. Arch Surg 1991;126:991–996.

    Article  CAS  PubMed  Google Scholar 

  23. Singh JP, Kashyap A. A comparative evaluation of percutaneous catheter drainage for resistant amebic liver abscesses. Am J Surg 1989;158:58–62.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Onkar Singh.

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Singh, O., Gupta, S., Moses, S. et al. Comparative study of catheter drainage and needle aspiration in management of large liver abscesses. Indian J Gastroenterol 28, 88–92 (2009). https://doi.org/10.1007/s12664-009-0032-1

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  • DOI: https://doi.org/10.1007/s12664-009-0032-1

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