Abstract
Objectives
Temporomandibular joint disorders (TMDs) are progressive disorders which lead to development of arthralgia and functional disabilities of temporomandibular joint. The treatment of the TMDs is controversial; noninvasive and minimally invasive therapies have shown a success rate of 70 to 85% for its management. The objective of present study is to evaluate and compare the efficacy of intra-articular platelet-rich plasma (PRP) and arthrocentesis in management of TMDs.
Materials and Methods
Twenty-four patients with complaint of reduced mouth opening, joint noise, pain, jaw deviation, not responding to medicinal treatment and coming under group II/III of RDC/TMD were included. Patients were randomly and equally divided in two groups. In group A, arthrocentesis was performed, whereas group B patients underwent intra-articular injections of PRP. Patients were clinically evaluated preoperatively to 12 months postoperatively.
Result
Both the groups showed significant improvement in painless mouth opening (P < 0.01), lateral movements towards unaffected side (P < 0.05) and reduction in pain complaint (P < 0.01). Arthrocentesis group also showed significant improvement in maximum mouth opening (P < 0.01).
Conclusion
On comparison, both groups were found to have effective treatment modality. However, arthrocentesis has higher success rate for pain elimination, and PRP is more effective in correction of joint noise and jaw deviation.
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Abbreviations
- TMJ:
-
Temporomandibular joint
- TMDs:
-
Temporomandibular joint disorders
- RDC:
-
Research diagnostic criteria
- PRP:
-
Platelet-rich plasma
- HA:
-
Hyaluronic acid
- OPG:
-
Orthopantomography
- VAS:
-
Visual analogue scale
- PMO:
-
Painless mouth opening
- MMO:
-
Maximal mouth opening
- LMTUS:
-
Lateral movemeents towards opposite side
- HH:
-
Holmlund–Hellsing
- Fig:
-
Figure
- PPP:
-
Platelet-poor plasma
- Et al.:
-
And others
- %:
-
Percentage
- RL:
-
Ringer’s lactated
References
Hassan EF, Ali TM, Abdulla N (2016) The clinical efficiency of platelet rich plasma in the treatment of temporomandibular joint disorders. Alex Dent J 41(3):226–231
Hancı M, Karamese M, Tosun Z, Aktan TM, Duman S, Savaci N (2015) Intra-articular platelet-rich plasma injection for the treatment of temporomandibular disorders and a comparison with arthrocentesis. J Cranio Maxillofac Surg 43(1):162–166
Hosgor H, Bas B, Celenk C (2017) A comparison of the outcomes of four minimally invasive treatment methods for anterior disc displacement of the temporomandibular joint. Int J Oral Maxillofac Surg 46(11):1403–1410
Okeson JP (2014) Management of temporomandibular disorders and occlusion-E-book. Elsevier, Amsterdam
Dworkin SF, LeResche L (1992) Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique. J Craniomandib Disord Facial Oral Pain 6(4):301
Bessa-Nogueira RV, Vasconcelos BC, Niederman R (2008) The methodological quality of systematic reviews comparing temporomandibular joint disorder surgical and non-surgical treatment. BMC Oral Health 8(1):27
Fouda AA (2018) Association between intra-articular corticosteroid injection and temporo-mandibular joint structure changes. Int Arch Oral Maxillofac Surg 2:015
Guarda-Nardini L, Tito R, Staffieri A, Beltrame A (2002) Treatment of patients with arthrosis of the temporomandibular joint by infiltration of sodium hyaluronate: a preliminary study. Eur Arch Otorhinolaryngol 259(5):279–284
Cerza F, Carnì S, Carcangiu A, Di Vavo I, Schiavilla V, Pecora A et al (2012) Comparison between hyaluronic acid and platelet-rich plasma, intra-articular infiltration in the treatment of gonarthrosis. Am J Sports Med 40(12):2822–2827
Hegab AF, Ali HE, Elmasry M, Khallaf MG (2015) Platelet-rich plasma injection as an effective treatment for temporomandibular joint osteoarthritis. J Oral Maxillofac Surg 73(9):1706–1713
Neeli AS, Umarani M, Kotrashetti SM, Baliga S (2010) Arthrocentesis for the treatment of internal derangement of the temporomandibular joint. J Maxillofac Oral Surg 9(4):350–354
Nitzan DW, Dolwick MF, Martinez GA (1991) Temporomandibular joint arthrocentesis: a simplified treatment for severe, limited mouth opening. J Oral Maxillofac Surg 49(11):1163–1167
Kiliç SC, Güngörmüş M, Sümbüllü MA (2015) Is arthrocentesis plus platelet-rich plasma superior to arthrocentesis alone in the treatment of temporomandibular joint osteoarthritis? A randomized clinical trial. J Oral Maxillofac Surg 73(8):1473–1483
Scrivani SJ, Keith DA, Kaban LB (2008) Temporomandibular disorders. N Engl J Med 359(25):2693–2705
Tvrdy P, Heinz P, Pink R (2015) Arthrocentesis of the temporomandibular joint: a review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 159(1):31–34
Do Egito Vasconcelos BC, Bessa-Nogueira RV, Rocha NS (2006) Temporomandibular joint arthrocententesis: evaluation of results and review of the literature. Braz J Otorhinolaryngol 72(5):634–638
Shinjo H, Nakata K, Shino K, Hamada M, Nakamura N, Mae T, Miyama T, Horibe S, Yoshikawa H, Ochi T (2002) Effect of irrigation solutions for arthroscopic surgery on intraarticular tissue: comparison in human meniscus-derived primary cell culture between lactate Ringer’s solution and saline solution. J Orthop Res 20(6):1305–1310
Zardeneta G, Milam SB, Schmitz JP (1997) Elution of proteins by continuous temporomandibular joint arthrocentesis. J Oral Maxillofac Surg 55(7):709–716
Guarda-Nardini L, Manfredini D, Ferronato G (2008) Arthrocentesis of the temporomandibular joint: a proposal for a single-needle technique. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol 106(4):483–486
Dimitroulis G, Dolwick MF, Martinez A (1995) Temporomandibular joint arthrocentesis and lavage for the treatment of closed lock: a follow-up study. Br J Oral Maxillofac Surg 33(1):23–27
Dıraçoğlu D, Saral İB, Keklik B, Kurt H, Emekli U, Özçakar L, Karan A, Aksoy C (2009) Arthrocentesis versus nonsurgical methods in the treatment of temporomandibular disc displacement without reduction. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol 108(1):3–8
Vos LM, Slater JH, Stegenga B (2014) Arthrocentesis as initial treatment for temporomandibular joint arthropathy: a randomized controlled trial. J Cranio Maxillofac Surg 42(5):e134–e139
Machoň V, Řehořová M, Šedý J, Foltán R (2013) Platelet-rich plasma in temporomandibular joint osteoarthritis therapy: a 3-month follow-up pilot study. J Arthritis 2(2):2–5
Pihut M, Szuta M, Ferendiuk E, Zeńczak-Więckiewicz D (2014) Evaluation of pain regression in patients with temporomandibular dysfunction treated by intra-articular platelet-rich plasma injections: a preliminary report. BioMed Res Int. https://doi.org/10.1155/2014/132369
Lin SL, Tsai CC, Wu SL, Ko SY, ChiangWF Yang JW (2018) Effect of arthrocentesis plus platelet-rich plasma and platelet-rich plasma alone in the treatment of temporomandibular jointosteoarthritis. Medicine 97(16):e0477
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All authors whose names appear on the submission (1) made substantial contributions to the conception or design of the work or the acquisition, analysis, or interpretation of data used in the work, (2) drafted the work or revised it critically for important intellectual content, (3) approved the version to be published, and (4) agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by AR. The first draft of the manuscript was written by AR, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. VB and AR helped in conceptualization. VB, PD and AR contributed to methodology. AR was involved in formal analysis and investigation. AR contributed to writing—original draft preparation. VB, PD and Dr Ankit Kapoor contributed to writing—review and editing. VB contributed to resources. VB and PD were involved in supervision. VB and PD helped in validation. AR, VB, PD and AK helped in visualization. AR contributed to data curation. AR and AK performed formal analysis. AR and VB were involved investigation. VB and PD helped in project administration.
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Rajput, A., Bansal, V., Dubey, P. et al. A Comparative Analysis of Intra-articular Injection of Platelet-Rich Plasma and Arthrocentesis in Temporomandibular Joint Disorders. J. Maxillofac. Oral Surg. 21, 168–175 (2022). https://doi.org/10.1007/s12663-020-01351-w
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DOI: https://doi.org/10.1007/s12663-020-01351-w