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The location and morphometry of the thyroid isthmus in adult Korean cadavers

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Abstract

The thyroid isthmus has different measurements in its width, height, and thickness, and its location with respect to the tracheal rings has been inconsistent, among the anatomical literature. This study was performed to clarify the location and morphometric characteristics of the thyroid isthmus. One hundred thyroid isthmuses of adult Korean cadavers (gender 58 males and 42 females, mean age 62.9 years, range 19–94 years) were used for this study. The distances from the inferior border of the cricoid cartilage to the superior and inferior margins of the isthmus were 4.9 ± 3.7 and 20.8 ± 5.8 mm, respectively. The width, height, and thickness of the thyroid isthmus were 11.1 ± 6.2, 15.9 ± 5.8 and 3.4 ± 1.7 mm, respectively. The thyroid isthmus was located on the 2nd to 4th, 1st to 3rd, and 1st to 4th tracheal rings, in 22, 18 and 18 % of the specimens, respectively. These results are expected to further the current knowledge of the location and morphometry of the thyroid isthmus and provide helpful information for surgical procedures in this region.

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References

  • Anson BJ (1996) Morris’ human anatomy, 12th edn. McGraw-Hill book Co, New York

    Google Scholar 

  • Braun EM, Windisch G, Wolf G, Hausleitner L, Anderhuber F (2007) The pyramidal lobe: clinical anatomy and its importance in thyroid surgery. Surg Radiol Anat 29:21–27

    Article  PubMed  Google Scholar 

  • Clemente CD (1985) Anatomy of the human body, 30th edn. Lea & Febiger, Philadelphia

    Google Scholar 

  • DeGroot LJ, Jameson JL, Burger HG, et al. (2001) Thyroid gland. In: DeGroot LJ (ed) Endocrinology, vol 2. 4th edn. W.B. Saunders Company, Philadelphia, pp 1268–1615

  • Dixit D, Shilpa MB, Harsh MP, Ravishankar MV (2009) Agenesis of isthmus of thyroid gland in adult human cadavers: a case series. Cases J 20:6640

    Article  Google Scholar 

  • Gardner E, Gray DJ, O’Rahilly R (1960) Anatomy, a regional study of human structure. W.B. Saunders Company, Philadelphia

    Google Scholar 

  • Harjeet A, Sahni D, Jit I, Aggarwal AK (2004) Shape, measurements and weight of the thyroid gland in northwest Indians. Surg Radio Anat 26:91–95

    Article  CAS  Google Scholar 

  • Joshi SD, Joshi SS, Daimi SR, Athavale SA (2010) The thyroid gland and its variations: a cadaveric study. Folia Morphol 69:47–50

    CAS  Google Scholar 

  • Marshall CF (1895) Variations in the form of the thyroid gland in man. J Anat Physiol 29:234–239

    PubMed  CAS  Google Scholar 

  • Moore KL, Dalley AF, Agur AM (2010) Clinically oriented anatomy, 6th edn. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  • Nixon IJ, Palmer FL, Whitcher MM et al (2011) Thyroid isthmusectomy for well-differentiated thyroid cancer. Ann Surg Oncol 18:767–770

    Article  PubMed  Google Scholar 

  • Ozgur Z, Celik S, Govsa F, Ozgur T (2011) Anatomical and surgical aspects of the lobes of the thyroid glands. Eur Arch Otorhinolaryngol 268:1357–1363

    Article  PubMed  Google Scholar 

  • Pastor Vázquez JF, Gil Verona JA, De Paz Fernández FJ, Barbosa Cachorro M (2006) Agenesis of the thyroid isthmus. Eur J Anat 10:83–84

    Google Scholar 

  • Ranade AV, Rai R, Pai MM et al (2008) Anatomical variations of the thyroid gland: possible surgical implications. Singap Med J 49:831–834

    CAS  Google Scholar 

  • Romanes GJ (1995) Cunningham’s textbook of anatomy, 12th edn. Oxford University Press, Oxford

    Google Scholar 

  • Rosse C, Gaddum-Rosse P (1997) Hollinshead’s text book of anatomy, 5th edn. Lippincott-Raven, Philadelphia

    Google Scholar 

  • Şeker S, Taş İ (2010) Determination of thyroid volume and its relation with isthmus thickness. Eur J Gen Med 7:125–129

    Article  Google Scholar 

  • Skilbeck C, Leslie A, Simo R (2007) Thyroid isthmusectomy: a critical appraisal. J Laryngol Otol 121:986–989

    Article  PubMed  CAS  Google Scholar 

  • Standring S (2008) Head and Neck. In: Standring S, Borley NR, Collins P et al (eds) Gray’s anatomy: the anatomical basis of clinical practice, 40th edn. Churchill Livingstone, Philadelphia, pp 395–704

    Google Scholar 

  • Sultana SZ, Khalil M, Khan MK et al (2011) Morphometry of isthmus of thyroid gland in Bangladeshi cadaver. Mymensingh Med J 20:366–370

    PubMed  CAS  Google Scholar 

  • Tong ECK, Rubenfeld S (1972) Scan measurements of normal and enlarged thyroid gland. Am J Roentgenol Radium Ther Nucl Med 115:706–708

    Article  PubMed  CAS  Google Scholar 

  • Wahl RA, Vorländer C, Kriener S, Pedall J, Spitza M, Hansmann ML (2006) Isthmus-preserving total bilobectomy: an adequate operation for C-cell hyperplasia. World J Surg 30:860–871

    Article  PubMed  Google Scholar 

  • Won HS, Chung IH (2002) Morphologic variations of the thyroid gland in Korean adults. Korean J Phys Antropol 15:119–125 (in Korean with English abstract)

    Google Scholar 

  • Woodburne RT, Burkel W (1994) Essentials of human anatomy, 9th edn. Oxford University Press, New York

    Google Scholar 

Download references

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Correspondence to Chang-Seok Oh.

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Won, HS., Han, SH., Oh, CS. et al. The location and morphometry of the thyroid isthmus in adult Korean cadavers. Anat Sci Int 88, 212–216 (2013). https://doi.org/10.1007/s12565-013-0187-9

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  • DOI: https://doi.org/10.1007/s12565-013-0187-9

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