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Comorbid conditions in individuals assessed by SPECT: Study of a reference cardiology center in Mexico City

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Journal of Nuclear Cardiology Aims and scope

Abstract

Background

There is an increasing prevalence of comorbidities in patients with ischemic heart disease (IHD) in developing countries. The aim of this work is to assess the prevalence of comorbidities and associated factors for IHD among patients at a reference cardiology center.

Design and Methods

This was a cross-sectional study. A complete clinical history which focused on the main comorbidities, previous myocardial infarction, and the main reason of referral was assessed. A single-photon emission computed tomography (SPECT) myocardial perfusion study (MPS) with two protocols was performed.

Results

We included 1998 patients, 64.2% male, median age 63 (I.R.: 56–71) years. 1514 (75.8%) subjects had at least one associated comorbidity. The main comorbidity was diabetes (T2D) (772: 38.6%), followed by systemic hypertension (737: 36.9%), smoking (518: 25.9%), and dyslipidemia (517: 25.9%). 806 (40.3%) had histories of previous myocardial infarctions. The main cause of referral was angina (923: 46.2%). We identified 1330 (66.5%) abnormal MPS. 460 (23%) had ischemia, 292 (14.6%) infarction, and 578 (28.9%) ischemia and infarction.

Conclusion

An increased prevalence of comorbidities was found in patients who were studied in the Nuclear Cardiology Department (NCD): most of them had traditional risk factors attributable to myocardial infarction. A great percentage were newly diagnosed with both ischemia and infarction.

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Abbreviations

CVD:

Cardiovascular diseases

T2D:

Type 2 diabetes

ENSANUT:

National Health and Nutrition Survey

PTCA:

Percutaneous coronary angioplasty

MPS:

Myocardial perfusion study

SPECT:

Single-photon emission computed tomography

NYHA:

New York Heart Association

NCD:

Nuclear Cardiology Department

IHD:

Ischemic heart disease

CMD:

Coronary multivessel disease

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Acknowledgments

The authors would like to thank the entire staff of the Nuclear Cardiology Department at Instituto Nacional de Cardiologia Ignacio Chavez, particularly the nurses and technicians. Neftali Eduardo Antonio-Villa is enrolled in the PECEM program of the Faculty of Medicine at UNAM. Dr. Candace Keirns made the native speaker review of the manuscript.

Author Contributions

NEAV: Research idea, study design, data acquisition, data analysis, statistical analysis, manuscript drafting. NEZ: Research idea, study design, data analysis, statistical analysis, manuscript drafting, supervision, and mentorship. ICJ: Research idea, study design, data analysis, manuscript drafting. ANGF: Research idea, study design, data analysis, manuscript drafting. EAR: Research idea, study design, data analysis, statistical analysis, manuscript drafting, supervision, and mentorship.

Disclosures

The authors declare that they have no conflict of interests.

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Author notes

  1. Neftali Eduardo Antonio-Villa and Nilda Espínola-Zavaleta contributed equally to the preparation of this paper.

Authors and Affiliations

  1. Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

    Neftali Eduardo Antonio-Villa MD/PhD (PECEM) Program

  2. Nuclear Cardiology Department, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, Colonia Seccion XVI, Tlalpan, P. C. 14030, Mexico City, Mexico

    Nilda Espínola-Zavaleta MD, PhD, Isabel Carvajal-Juárez MD, Alondra Noe Flores-Garcia MD & Erick Alexanderson-Rosas MD

  3. PET/CT Ciclotrón, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

    Isabel Carvajal-Juárez MD

  4. Physiology Department, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico

    Erick Alexanderson-Rosas MD

Authors
  1. Neftali Eduardo Antonio-Villa MD/PhD (PECEM) Program
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Corresponding author

Correspondence to Erick Alexanderson-Rosas MD.

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Antonio-Villa, N.E., Espínola-Zavaleta, N., Carvajal-Juárez, I. et al. Comorbid conditions in individuals assessed by SPECT: Study of a reference cardiology center in Mexico City. J. Nucl. Cardiol. 26, 1617–1624 (2019). https://doi.org/10.1007/s12350-019-01737-5

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  • DOI: https://doi.org/10.1007/s12350-019-01737-5

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