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The effects of surgical repair on P-wave dispersion in children with secundum atrial septal defect

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Abstract

Introduction

Atrial septal defect (ASD) is one of the most common congenital heart diseases in children. P-wave dispersion has been reported to be associated with non-homogeneous propagation of sinus impulses. The heterogeneity of atrial conduction time may predispose the atria to arrhythmias. The aim of this study was to determine the impact of surgical repair on P-wave indices in children with isolated secundum ASD.

Methods

Children with isolated secundum ASD undergoing surgical repair (n=50; mean age, 7.0±3.0 years) and healthy controls (n=51; mean age, 7.6±2.7 years) were compared. Maximum P-wave duration (Pmax), shortest duration (Pmin) and P-wave dispersion (Pd) were measured using 12-lead surface electrocardiography.

Results

Mean Pmax was found to be significantly higher in children with ASD compared with controls (95.2±10.8 vs 84.1±9.2 msec; P<0.001), and Pd before surgery was significantly higher compared with controls (47.4±12.0 vs 38.8±9.7 msec; P<0.001). Both P-wave indices were significantly decreased within the first year after surgical closure — the values decreased to those comparable to healthy controls (Pmax, 86.2±9.7 msec; Pd, 39.8±10.7 msec; P>0.05).

Conclusion

Surgical closure of ASD in children decreases Pmax and P-wave conduction time. We speculate that earlier closure of the defect may play an important role in avoiding permanent changes in the atrial myocardium and atrial fibrillation in adulthood.

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Authors and Affiliations

  1. Department of Paediatrics, Duzce Faculty of Medicine, Duzce, Turkey

    Taner Yavuz

  2. Department of Paediatric Cardiology, Istanbul Faculty of Medicine, Istanbul, Turkey

    Kemal Nisli, Naci Oner, Aygun Dindar, Umrah Aydogan, Rukiye Eker Omeroglu & Turkan Ertugrul

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  1. Taner Yavuz
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  2. Kemal Nisli
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  3. Naci Oner
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  7. Turkan Ertugrul
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Correspondence to Taner Yavuz.

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Yavuz, T., Nisli, K., Oner, N. et al. The effects of surgical repair on P-wave dispersion in children with secundum atrial septal defect. Adv Therapy 25, 795–800 (2008). https://doi.org/10.1007/s12325-008-0081-3

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