Abstract
Fasting samples of 914 subjects from healthy population were analyzed for total cholesterol, triglyceride and three major fractions of lipoproteins i.e. high-density lipoprotein cholesterol, low lipoprotein cholesterol and very low-density lipoprotein cholesterol. The values obtained were (in mg/dl) 165.7±30.2,88.36±31.2, 44.86±10.68, 101.66±29.8 and 18.11±7.35 respectively. When these subjects were grouped according to the age and sex, no appropriate differences were observed between most of the groups. Triglycerides were found to be low and HDL cholesterol was high in female when compared with male of similar age. Beyond age 40 years cholesterol level and low density lipoprotein cholesterol was found to be gradually increased in case of women. Minor difference was observed with dietary pattern. Present study suggests that clinical evaluation of patient should be made on the basis of these reference values for Western Maharashtra population.
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References
Solberg H. International Federation of Clinical Chemistry Expert panel on theory of reference Values: Part I- The concepts of Reference values J Clin Chem Clin Biochem 1987; 25: 337–342, 639–44.
Gandhi BM. Lipoprotein composition of normal healthy subjects in northern India. Ind J Med Res 1982; 75: 393–401.
Goswami K, Bandopadhyay A. Lipid profile in middle class Bengali population of Kolkata. Ind J Clin Biochem 2003; 18: 131–135.
Jhala CI, Shah UV, Shah TK, Naik BK, Dafda JD. A study of serum Lipid profile part I: establishment of Normal reference Values of Serum lipid levels in Healthy vegetarian population of Gujarat. Ind J Clin Biochem 1988; 13: 1–7.
Martin Bland. An Introduction to Medical Statistics. Oxford University Press, 3rd edition. 2000; 343.
Solberg H. International Federation of Clinical Chemical Expert Panel on theory of reference values; Approved recommendation on the theory of reference values. Part 5 statistical treatment of collected reference values: Determination of reference limits. J Chem Clin Biochem 1987; 25: 645–656.
National Cholesterol Education program. Second report of the expert panel on detection evaluation and treatment of High blood cholesterol in adults (Adults treatment panel — II) Circulation 1994; 89: 1329–1445.
Ramani A, Bilgrami NL, Kumar S. Morbidity and mortality of acute myocardial infarction in and around Aligarh. J Ind Med Assoc 1990; 88: 192–195.
Ashavaid T, Todur SP, Dherai AJ. Health status of Indian Population-current scenario. JAPI 2004; 52: 363–369.
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Durgawale, P., Patil, S., Shukla, P.S. et al. Evaluation of reference intervals of serum lipid profile from healthy population in Western Maharashtra. Indian J Clin Biochem 24, 30–35 (2009). https://doi.org/10.1007/s12291-009-0005-2
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DOI: https://doi.org/10.1007/s12291-009-0005-2