Abstract
Complete trisomy 9 is a rare cytogenetic abnormality in haematological malignancies. Here we present the case history of a patient with clinical diagnosis of acute myeloblastic leukaemia (FAB type M2) and having trisomy 9 with adverse outcome.
This is a preview of subscription content, log in via an institution to check access.
References
United Kingdom Cancer Cytogenetics Group (UKCCG) (1992) Primary, single autosomal trisomies associated with haematological disorders. Leukemia Res 16:841–851
Grimwade D, Walker H, Oliver F et al (1998) The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. Blood 92:2322–2333
Sole F, Luno E, Sanzo C et al (2005) Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes. Haematologica 90:1168–1178
Zhang L, Yang W, Hubbard AE et al (2005) Nonrandom aneuploidy of chromosomes 1, 5, 6, 7, 8, 9, 11, 12, and 21 induced by the benzene metabolites hydroquinone and benzenetriol. Environ Mol Mutagen 45:388–396
Bench AJ, Nacheva EP, Champion KM et al (1998) Molecular genetics and cytogenetics of myeloproliferative disorders. Baillieres Clin Haematol 11:819–848
Shaffer LG, Tommerup N (2005) Recommendations of the International Standing Committee on Human Cytogenetic Nomenclature. Published in collaboration with ‘Cytogenetic and GenomeResearch’. International System for Human Cytogenetic Nomenclature
Kor-Anantakul O, suwanrath C, Kannngurn S et al (2006) Prenatal diagnosis of complete trisomy 9: a case report and review of the literature. Am J Perinatol 23:131–135
Ferreres JC, Planas S, Martínez-Sáez EA et al (2008) Pathological findings in the complete trisomy 9 syndrome: three case reports and review of the literature. Pediatr Dev Pathol 11:23–29
Pinette MG, Pan Y, Chard R, Blackstone J et al (1987) Prenatal diagnosis of nonmosaic trisomy 9 and related ultrasound findings at 11.7 weeks. J Matern Fetal Med 48–50
Póvoa A, Ramalho C, Torgal A et al (2008) Positive biochemical screening for trisomy 18: on the path of trisomy 9. Prenat Diagn 28:162–164
Mark HF, Gray Y, Sotomayor E (1999) Trisomy 9 in a patient with secondary acute myelogenous leukemia detected by fluorescent in situ hybridization. Pathobiology 67:111–114
Acknowledgment
The first author (R.Chaubey) acknowledges the Indian Council for Medical Research (ICMR), New Delhi, for the research fellowship.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Chaubey, R., Sazawal, S., Dada, R. et al. Trisomy 9 in a Patient with Acute Myelogenous Leukaemia FAB Type M2: A Rare Occurrence. Indian J Hematol Blood Transfus 26, 103–105 (2010). https://doi.org/10.1007/s12288-010-0035-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12288-010-0035-1