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Procedures for location of non-palpable breast lesions: a systematic review for the radiologist

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Abstract

Accurate location of small breast lesions is mandatory for proper surgical management. The purpose of this article is systematically review procedures used to locate non-palpable breast lesions, including a description of the current status, advantages, and disadvantages for each technique. A total of 47 articles were finally included: 7 articles for the wire location technique, 5 articles for the radioguided location technique, 13 articles that compare wire location with radioguided location, 3 articles for the carbon location technique, 2 articles that compare wire location with carbon location, and 17 articles for the clip location technique. The success of location and the clear margin are reported for each location technique and for the separate articles included; clip migration shift, also, is reported for the clip location technique. Odds ratio with related 95 % confidence intervals were also calculated for successful location. Comparative analysis or meta-analysis for all the different breast lesion location techniques is missing. Prospective investigations and randomized investigations for homogeneous populations are still needed to determine which is the most cost-effective modality among those used to date.

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Abbreviations

CI:

Confidence interval

CL:

Carbon location

MRI:

Magnetic resonance imaging

ROLL:

Radioguided occult location

WL:

Wire location

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Acknowledgments

The authors are grateful to Alessandra Trocino, librarian at the National Cancer Institute “G. Pascale” of Naples, Italy, for bibliographic assistance.

Conflict of interest

The authors declare that they have no competing interests. The authors have no conflict of interest to be disclosed.

Author contribution

RF works on literature search, statistical analysis and drafting of the manuscript in collaboration with AP. OC,VG and SF participated in the drafting the manuscript. MS participated in the design of the study and performed the statistical analysis. MD, QP and MDA conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.

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Authors and Affiliations

  1. Department of Diagnostic Unit, National Cancer Institute, Pascale Foundation, via M. Semmola, 80131, Naples, Italy

    Roberta Fusco, Antonella Petrillo, Orlando Catalano, Vincenza Granata & Salvatore Filice

  2. Department of Biomedical, Electronics and Telecommunications Engineering, University “Federico II” of Naples, via Claudio, 21, 80132, Naples, Italy

    Roberta Fusco & Mario Sansone

  3. Division of Breast Surgery, Department of Breast Surgery and Oncology, National Cancer Institute, Pascale Foundation, via M. Semmola, 80131, Naples, Italy

    Massimiliano D’Aiuto

  4. Davy-Faraday Research Laboratory, The Royal Institute of Great Britain, 21 Albermarle Street, London, W1S 4BS, UK

    Quentin Pankhurst

  5. Department of Research Oncology, King’s College London, London, SE1 9RT, UK

    Michael Douek

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  1. Roberta Fusco
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  2. Antonella Petrillo
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  3. Orlando Catalano
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  4. Mario Sansone
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  5. Vincenza Granata
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  6. Salvatore Filice
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  7. Massimiliano D’Aiuto
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  8. Quentin Pankhurst
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  9. Michael Douek
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Corresponding author

Correspondence to Antonella Petrillo.

Additional information

R. Fusco and A. Petrillo contributed equally to this work.

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Fusco, R., Petrillo, A., Catalano, O. et al. Procedures for location of non-palpable breast lesions: a systematic review for the radiologist. Breast Cancer 21, 522–531 (2014). https://doi.org/10.1007/s12282-012-0427-1

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  • DOI: https://doi.org/10.1007/s12282-012-0427-1

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