Abstract
Background
Mammography and physical examination (PE) are the recommended modalities for breast-cancer screening for women 40 years and older in Japan. Mammography, however, cannot detect lesions in dense breast tissue, which is common in Japanese women. Breast screening by ultrasound (US) is popular in Japan. We studied which modality or combinations of modalities optimize breast cancer detection for Japanese women.
Methods
From April 1993 through March 2005 we found 97 breast cancers in 9,082 women by screening examinations with mammography, US, and PE. We compared the detection rates of these three modalities for breast cancer.
Results
The detection rates of mammography, US, and PE for breast cancer were 83.5 (81 of 97 cancers), 75.3 (73 of 97 cancers), and 60.8% (59 of 97 cancers), respectively. The detection rates of the combinations of mammography and US, mammography and PE, and US and PE were 99.0 (96 of 97 cancers), 88.7 (86 of 97 cancers), and 81.4% (79 of 97 cancers), respectively. Ultrasonography detected 15% of the mammographically occult breast cancers.
Conclusion
Screening with the combination of mammography and US significantly increases the detection rate of breast cancer. These results suggest that screening with mammography and US would optimize cancer detection in Japanese women.
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Abbreviations
- US:
-
Ultrasonography
- PE:
-
Physical examination
References
Mammography Guidelines, 2nd ed. Tokyo: Igakushoin; 2004.
Kerlikowske K, Grady D, Rubin SM, Sandrock C, Emster VL. Efficacy of screening mammography. A meta-analysis. JAMA. 1995;273:149–54.
Kolb TM, Lichy J, Newhouse JH. Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. Radiology. 2001;225(1):165–75.
Edeiken S. Mammography and palpable cancer of the breast. Cancer. 1988;61:263–5.
Tarter PI, Weiss S, Armed S, Kamath S, Hermann G, Drossman S. Mammographically occult breast cancers. Breast J. 1999;5(1):22–5.
Namba K, Watanabe R, Furusawa H, Matsu T, Shirouzu M, Tanaka C, Hirokaga K, Masuda T, Takahashi M, Namba S. Significance of breast cancer screening by mammography and ultrasound for women aged 49 and under. J Jpn Assoc Breast Cancer Screen. 2002;11(2):172–7.
Takahashi K, Nishimura S, Tanaka K, Higa J, Makita M, Yoshimoto M, Kasumi F, Sakuma H, Akiyama F, Sakamoto G. Role of mammography and ultrasound in breast cancer screening for women in their 40s. Jpn Assoc Breast Cancer Screen. 2002;11(3):341.
Ma L, Fishell E, Wright B, Hanna W, Allan S, Bovd NF. Case-control study of factors associated with failure to detect breast cancer by mammography. J Natl Cancer Inst. 1992;84(10):781–5.
Tohno E, Ueno E. Ultrasound (US) diagnosis of nonpalpable breast cancer. Breast Cancer. 2005;12(4):267–71.
Gordon PB, Goldenberg AL. Malignant breast masses detected only by ultrasound. A retrospective review. Cancer. 1995;76(4):626–30.
Buchberger W, Niehoff A, Obrist P, Dekoekkoek-Doll P, Duncer M. Clinically and mammographically occult breast lesions: detection and classification with high-resolution sonography. Semin Ultrasound CT MR. 2000;21(4):325–36.
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Uchida, K., Yamashita, A., Kawase, K. et al. Screening ultrasonography revealed 15% of mammographically occult breast cancers. Breast Cancer 15, 165–168 (2008). https://doi.org/10.1007/s12282-007-0024-x
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DOI: https://doi.org/10.1007/s12282-007-0024-x