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The rationale and potential for using Lactobacillus in the management of periodontitis

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A Publisher Erratum to this article was published on 01 April 2022

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Abstract

Periodontitis refers to a wide range of the inflammatory conditions of supporting dental structures. For some patients with periodontitis, antibacterial agents are needed as an adjuvant to mechanical debridement treatments and oral hygiene maintenance. However, the widespread use of broad-spectrum antibiotics for the prophylaxis and treatment of periodontal infections results in the emergence of resistant pathogens. Therefore, probiotics have become markedly interesting to researchers as a potentially safe alternative to periodontal treatment and maintenance. Probiotics have been used in medicine for decades and extensively applied to the treatment of inflammatory diseases through the modulation of microbial synergy and other mechanisms. A growing amount of evidence has shown that using Lactobacillus strains for oral cavity maintenance could improve periodontal health. In this study, we reviewed studies showing proof of the inhibitory effects of Lactobacillus species on periodontal inflammation. We also explored the rationale and potential for using Lactobacillus species in the management of periodontitis.

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Acknowledgements

This research was funded by Natural Science Foundation of Liaoning Province (20180551232) and Science and Technology Project of Shenyang (F16-102-4-00).

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Authors and Affiliations

  1. Department of Periodontics, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110122, P. R. China

    Jiaqi Wang, Yingman Liu, Weiru Wang, Jiaojiao Ma & Yurong Kou

  2. Department of Oral Biology, School and Hospital of Stomatology, China Medical University, Liaoning Provincial Key Laboratory of Oral Diseases, Shenyang, 110122, P. R. China

    Manman Zhang, Xiaoying Lu & Yurong Kou

  3. Science Experiment Center, China Medical University, Shenyang, 110122, P. R. China

    Jie Liu

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  1. Jiaqi Wang
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  2. Yingman Liu
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  3. Weiru Wang
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  5. Manman Zhang
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  7. Jie Liu
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Correspondence to Yurong Kou.

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Wang, J., Liu, Y., Wang, W. et al. The rationale and potential for using Lactobacillus in the management of periodontitis. J Microbiol. 60, 355–363 (2022). https://doi.org/10.1007/s12275-022-1514-4

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  • DOI: https://doi.org/10.1007/s12275-022-1514-4

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