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New antimicrobial flavonoids and chalcone from Colutea armata

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Abstract

Colucins A (1) and B (2), new flavonoids and colucone (3), the new chalcone derivative, have been isolated from the CHCl3-soluble fraction of the whole plant of Colutea armata along with luteolin (4), luteolin 7-O-β-D-glucoside (5), isoliquiritigenin (6), trans-caffeic acid (7) and stigmasterol (8) reported for the first time from this species. Their structures were elucidated by spectroscopic techniques including MS and 2D-NMR spectroscopy. Compounds 1 and 2 showed significant antimicrobial activity against two Gram positive and three Gram negative bacterial strains while 3 was moderately active.

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Correspondence to Abdul Malik.

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Inamullah, F., Fatima, I., Khan, S. et al. New antimicrobial flavonoids and chalcone from Colutea armata . Arch. Pharm. Res. 40, 915–920 (2017). https://doi.org/10.1007/s12272-017-0901-6

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  • DOI: https://doi.org/10.1007/s12272-017-0901-6

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