Abstract
Chromatographic separation of the 80% MeOH extract of the leaves of Ilex rotunda (IR) led to isolation of two new hemiterpene glycosides, tentatively named as rotundarpenoside A (1) and rotundarpenoside B (2), along with five known caffeoyl derivatives (3–7). The chemical structures of these compounds were elucidated using 1D/2D NMR, HR-MS, and the absolute configuration was confirmed by Mosher’s method. In order to evaluate their anti-oxidative activities, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and xanthine oxidase superoxide scavenging activities (NBT) were determined.
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Kim, M.H., Park, K.H., Oh, M.H. et al. Two new hemiterpene glycosides from the leaves of Ilex rotunda. thunb. Arch. Pharm. Res. 35, 1779–1784 (2012). https://doi.org/10.1007/s12272-012-1010-1
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DOI: https://doi.org/10.1007/s12272-012-1010-1