Abstract
Two new cadinane-type sesquiterpenoids, scabralins A (1) and B (2) were obtained from the soft coral Sinularia scabra. Metabolite 1 was shown to exhibit moderate to weak cytotoxicity against MCF-7, WiDr, Daoy, and HEp 2 cancer cell lines. Also, incubation with 10 µM compound 1 significantly inhibited the accumulation of the pro-inflammatory inducible nitric oxide synthase protein in lipopolysaccharide-stimulated RAW264.7 macrophage cells.
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Su, JH., Huang, CY., Li, PJ. et al. Bioactive cadinane-type compounds from the soft coral Sinularia scabra . Arch. Pharm. Res. 35, 779–784 (2012). https://doi.org/10.1007/s12272-012-0503-2
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DOI: https://doi.org/10.1007/s12272-012-0503-2