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Synthesis of mono, bis-2-(2-arylideneaminophenyl) indole azomethines as potential antimicrobial agents

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Abstract

A series of mono and bis 2-2-(arylidineaminophenyl)indole azomethines have been synthesized by a condensation reaction of 2-(2-amino phenyl) indole with various mono and diketones R-CO-Rl /R-CO-X-CO-Rl (1:1/2:1 ratio) in ethanol media. The synthesized azomethines were characterized via IR, 1H-NMR, 13C-NMR, MS and elemental analysis. The antimicrobial activity of these compounds against different bacteria and fungi was also evaluated.

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Authors and Affiliations

  1. Department of Chemistry, Kakatiya University, Warangal, 506009, A.P, India

    Rondla Rohini, P. Muralidhar Reddy, Kanne Shanker, Kodipelli Kanthaiah & Vadde Ravinder

  2. Department of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien, 97004, Taiwan

    Rondla Rohini & Anren Hu

  3. Department of Chemistry, National Dong Hwa University, Hualien, 97441, Taiwan

    P. Muralidhar Reddy & Kanne Shanker

Authors
  1. Rondla Rohini
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  2. P. Muralidhar Reddy
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  3. Kanne Shanker
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  4. Kodipelli Kanthaiah
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  5. Vadde Ravinder
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  6. Anren Hu
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Correspondence to Vadde Ravinder or Anren Hu.

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Rohini, R., Reddy, P.M., Shanker, K. et al. Synthesis of mono, bis-2-(2-arylideneaminophenyl) indole azomethines as potential antimicrobial agents. Arch. Pharm. Res. 34, 1077–1084 (2011). https://doi.org/10.1007/s12272-011-0705-z

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  • DOI: https://doi.org/10.1007/s12272-011-0705-z

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