Abstract
A new eudesmanolide, 1β,3β-dihydroxy-eudesman-11(13)-en-6α,12-olide (1) was isolated and identified from Taraxacum mongolicum, together with two known compounds, 1β,3β-dihydroxyeudesman-6α,12-olide (2) and loliolide (3). The structure of 1 was established by analysis of its physical and spectroscopic data. 1 was found to have an inhibitory activity on nitric oxide production with an IC50 of 38.9 μM in activated RAW 264.7 cells.
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Kim, YH., Choo, SJ., Ryoo, IJ. et al. Eudesmanolides from Taraxacum mongolicum and their inhibitory effects on the production of nitric oxide. Arch. Pharm. Res. 34, 37–41 (2011). https://doi.org/10.1007/s12272-011-0104-5
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DOI: https://doi.org/10.1007/s12272-011-0104-5