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Perivascular space and neurological disorders

血맜周围间隙与神经系统疾病

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Abstract

Perivascular space (PVS) is a crevice between two slices of cerebral pia maters, filled with tissue fluid, which be formed by pia mater emboling in the surrounding of cerebral perforating branch (excluding micrangium). Normal PVS (diameter < 2 mm) can be found in almost all healthy adults; however enlarged PVS (diameter > 2 mm) has correlation with neurological disorders probably. The article reviews the formation mechanism, imageology characteristics and the relation with neurological disorders of PVS, which is beneficial to the research of some neurological disorders etiopathogenesis and treatment.

摘要

血맜周围间隙(Perivascular space, PVS)是软脑膜内陷在脑穿支小血맜周围(不包括毛细血맜)而形成的介于两层软脑膜之间的间隙, 其间充满组织液。正常PVS 的直径一般小于2 mm, 存在于几乎所有健康成年人, 而PVS 的直径增大超过2 mm, 则与多种神经系统疾病相关。本文就PVS 的形成机制、影像学特点及其与神经系统疾病的关系作了阐述, 这将对研究一系列神经系统疾病的发病机制和治疗方法有所助益。

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Authors and Affiliations

  1. Department of Internal Medicine, Beijing Obstetrics and Gynecology Hospital affiliated to Capital Medical University, Beijing, China

    Guan Wang  (王 冠)

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  1. Guan Wang  (王 冠)
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Correspondence to Guan Wang  (王 冠).

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Wang, G. Perivascular space and neurological disorders. Neurosci. Bull. 25, 33–37 (2009). https://doi.org/10.1007/s12264-009-1103-0

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  • DOI: https://doi.org/10.1007/s12264-009-1103-0

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