References
European Commission (1998) Report on osteoporosis in the European community: action for prevention. Office for Official Publications for the European Commission, Luxembourg
Gueguen R, Jouanny P, Guillemin F, Knutz C, Pourel J, Siset G (1995) Segregation analysis and variance components analysis on bone mineral density in healthy families. J Bone Miner Res 12:2017–2022
Wood RJ, Fleet JC (1998) The genetics of osteoporosis: vitamin D receptor polymorphisms. Annu Rev Nutr 18:233–258
Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, Sambrook PN, Eisman JA (1994) Prediction of bone density from vitamin D receptor alleles. Nature 367:284–287
Morrison NA, Qi JC, Tokita A, Kelly PJ, Crofts L, Nguyen TV, Sambrook PN, Eisman JA (1997) Prediction of bone density from vitamin D receptor alleles. Nature 387:106
Gross C, Eccleshall TR, Malloy PJ, Villa ML, Marcus R, Feldman D (1996) The presence of a polymorphism at the translation initiation site of the vitamin D receptor gene is associated with low bone mineral density in post-menopausal Mexican–American women. J Bone Miner Res 11:1850–1855
Arai H, Myamoto K, Taketani Y, Yamamoto H, Iemori Y, Morita K, Tonai T, Nishisho T, Mori S, Takeda E (1997) A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res 12:915–921
Eisman JA (2001) Pharmacogenetics of the vitamin D receptor and osteoporosis. Drug Metab Dispo 29:505–512
Cusack S, Cashman KD (2003) Impact of genetic variation on metabolic response of bone to diet. Proc Nutr Soc 62:901–912
Cooper GS, Umbach DM (1996) Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis. J Bone Miner Res 11:1841–1849
Gong G, Stern HS, Cheng SC, Fong N, Mordeson J, Deng HW, Recker RR (1999) The association of bone mineral density with vitamin D receptor gene polymorphisms. Osteoporos Int 9:55–64
Gennari L, Becherini L, Masi L, Mansani R, Gonnelli S, Cepollaro C, Martini S, Montagnani A, Lentini G, Becorpi AM, Brandi ML (1998) Vitamin D and estrogen receptor allelic variants in Italian postmenopausal women: evidence of multiple gene contribution to bone mineral density. J Clinl Endocrinol Metab 83:939–944
Willing M, Sowers M, Aron D, Clark MK, Burns T, Bunten C, Crutchfield M, D’Agostino D, Jannausch M (1998) Bone mineral density and its changes in white women: estrogen and vitamin D receptor genotypes and their interaction. J Bone Miner Res 13:695–705
Deng HW, Li J, Li JL, Johnson M, Gong G, Recker RR (1999) Association of VDR and estrogen receptor genotypes with bone mass in postmenopausal Caucasian women: different conclusions with different analyses and the implications. Osteoporos Int 9:499–507
Gennari L, Becherini L, Falchetti A, Masi L, Massart F, Brandi ML (2002) Genetics of osteoporosis: role of steroid hormone receptor gene polymorphisms. J Steroid Biochem Mol Biol 81:1–24
Institute of Medicine (1997) Dietary reference intakes: calcium, magnesium, phosphorus, vitamin D, and fluoride. Food and Nutrition Board, National Academy Press, Washington D.C
Ferrari S, Rizzoli R, Chevalley T, Slosman D, Eisman JA, Bonjour JP (1995) Vitamin D receptor gene polymorphisms and change in lumbar spine bone mineral density. Lancet 345:423–424
Krall EA, Parry P, Lichter JB, Dawson-Hughes B (1995) Vitamin D receptor alleles and rates of bone loss: influence of years since menopause and calcium intake. J Bone Miner Res 10:978–984
Macdonald H (2003) Nutrient-gene interactions influence the skeleton. In: New S, Bonjour P (eds)Nutritional aspects of bone health. Royal Society of Chemistry, Cambridge, pp 463–496
Kiel DP, Myers RH, Cupples LA, Kong XF, Zhu XH, Ordovas J, Schaefer EJ, Felson DT, Rush D, Wilson PWF, Eisman JA, Holick MF (1997) The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral density. J Bone Miner Res 12:1049–1057
Zittermann A (2003) Vitamin D in preventive medicine: are we ignoring the evidence? Br J Nutr 89:552–572
Graafmans WC, Lips P, Ooms ME, van Leeuwen JP, Pols HA, Uitterlinden AG (1997) The effect of vitamin D supplementation on the bone mineral density of the femoral neck is associated with vitamin D receptor genotype. J Bone Miner Res 12:203–205
Rapuri PB, Gallagher JC, Balhorn KE, Ryschon KL (2002) Smoking and bone metabolism in elderly women. Bone 27:429–436
Harrington M, Bennett T, Jakobsen J, Oresen L, Brot C, Flynn A, Cashman KD (2004) The effect of a high protein, high-sodium diet on calcium and bone metabolism in postmenopausal women and its interaction with vitamin D receptor genotype. Br J Nutr 91:41–51
Macdonald HM, McGuigan FE, Fraser WD, New SA, Ralston SH, Reid MD (2004) Methyltetrahydrofolate reductase polymporphism interacts with riboflavin intake to influence bone mineral density. Bone 35:957–964
Saupe J, Shearer MJ, Kohlmeier M (1993) Phylloquinone transport and its influence on y-carboxylation residues of osteocalcin in patients on maintenance haemodialysis. Am J Clin Nutr 58:204–208
Booth SL, Tucker KL, Chen H, Hannan MT, Gagnon DR, Cupples LA, Wilson PW, Ordovas J, Schaefer EJ, Dawson-Hughes B, Kiel DP (2000) Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr 71:1201–1208
Institute of Medicine (2001) Dietary reference intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium and zinc. National Academy Press, Washington DC
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Cashman, K.D., Seamans, K. Bone health, genetics, and personalised nutrition. Genes Nutr 2, 47–51 (2007). https://doi.org/10.1007/s12263-007-0010-0
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12263-007-0010-0