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Antibacterial properties of ferrimagnetic and superparamagnetic nanoparticles: a comparative study

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Abstract

In this study, antibacterial impact of magnetic nanocomposite (MNC: MoS2/CoFe2O4) and super paramagnetic iron oxide nanoparticle (SPION: Fe3O4-Casein) against staphylococcus aureus was studied. It was expected that such comparative study, address key points in optimization of synthesis and design of nanomaterials, which are supposed to be used as antibacterial agents for magnetic fluid hyperthermia (MFH) purposes. As the results, the MNC and SPION had average sizes of 17±4 nm and 15±5 nm, and diffused homogenously in agarose gel. They both were bacteriostatic against S. aureus at very low concentrations, while were bactericidal at concentrations of 200 µg/mL and more in MFH condition. In conclusion, both MNC and SPION inhibit S. aureus viability when low amplitude (H = 31.16 mT) alternative magnetic field (AMF: f = 150 kHz) was applied. Therefore, both of the nanomaterials are eligible to be considered as antibacterial candidates for treatment of complicated infections in upper respiratory tract or skin.

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Authors and Affiliations

  1. Department of Mechanical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran

    Mohammadhossein Shahsavari Alavijeh

  2. School of Mechanical Engineering, Iran University of Science and Technology, Tehran, Iran

    Milad Salimi Bani & Mohammad Haghpanahi

  3. Stem Cell Technology Research Center, Tehran, Iran

    Iman Rad

  4. Institute of Nano Engineering and MicroSystems, National Tsing Hua University, Hsinchu, 30013, Taiwan

    Shadie Hatamie

  5. National Institute of Genetic Engineering and Biotechnology, Tehran, Iran

    Mahsa Soufi Zomorod

Authors
  1. Mohammadhossein Shahsavari Alavijeh
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  2. Milad Salimi Bani
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  3. Iman Rad
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  4. Shadie Hatamie
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  5. Mahsa Soufi Zomorod
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  6. Mohammad Haghpanahi
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Corresponding authors

Correspondence to Iman Rad or Mohammad Haghpanahi.

Additional information

Mohammadhossein Shahsavari Alavijeh received his B.Sc. and Ph.D. degrees in Mechanical Engineering from Isfahan Universiy of Technology (IUT) and SRBIAU, Tehran, Iran, respectively. His research interests include Hyperthermia and Nano technology.

Iman Rad was born in Tehran, Iran, in 1983. He received the Bachelor’s and Master’s degrees in Cellular and Molecular Biology from University of Tehran and NIGEB, in 2005 and 2008, Iran, respectively, and Ph.D. in Biophysics from IBB, University of Tehran. His main interests include Cellular Biophysics, Computational Biology and bioelectromagnetics.

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Alavijeh, M.S., Bani, M.S., Rad, I. et al. Antibacterial properties of ferrimagnetic and superparamagnetic nanoparticles: a comparative study. J Mech Sci Technol 35, 815–821 (2021). https://doi.org/10.1007/s12206-021-0143-x

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  • DOI: https://doi.org/10.1007/s12206-021-0143-x

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