Abstract
Objective
The aim of this study was to compare health-related quality of life (HRQOL) between type 2 diabetic patients with and without locomotive syndrome, which is a risk for becoming bedridden because of deteriorating locomotive organs.
Subjects and methods
A total of 135 patients with type 2 diabetes mellitus (69.2 ± 10.2 years) were enrolled in this cross-sectional study. HRQOL was evaluated by the Euro-QOL-5 (EQ-5D), and locomotive syndrome was evaluated by “loco-check,” established the Japanese Orthopedic Association. Clinical data, such as anthropometric parameters, blood and urine examination results, blood pressure (BP), drug usage, and psychological distress, were analyzed.
Results
Average HbA1c in all patients was 7.2 ± 1.0 %, and 74 patients (54.8 %) were identified as having the locomotive syndrome. EQ-5D scores were significantly lower in type 2 diabetic patients with locomotive syndrome than in those without locomotive syndrome, even after adjusting for age, sex, body mass index (BMI), and HbA1c. By the multiple regression analysis, locomotive syndrome and age were identified as determinant factors of HRQOL in type 2 diabetic patients.
Conclusion
In type 2 diabetic patients, lower HRQOL was a characteristic feature of subjects with locomotive syndrome, even after adjusting for confounding factors. Prevention or management of locomotive syndrome may be beneficial for improving HRQOL in type 2 diabetic patients.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
http://www.mhlw.go.jp/stf/houdou/0000032074.html (2015.12.01) (in Japanese). Ministry of Health, Labor and Welfare:National health and nutrition examination Survey 2012.
Goto A, Noda M, Matsushita Y, Goto M, Kato M, Isogawa A, et al. Hemoglobin a1c levels and the risk of cardiovascular disease in people without known diabetes: a population-based cohort study in Japan. Medicine (Baltimore). 2015;94:e785.
Sakamaki H, Ikeda S, Ikegami N, Uchigata Y, Iwamoto Y, Origasa H, et al. Measurement of HRQL using EQ-5D in patients with type 2 diabetes mellitus in Japan. Val Health. 2006;9(1):47–53.
Nakamura KA. "Super-aged" society and the "locomotive syndrome". J Orthop Sci. 2008;13:1–2.
http://www.mhlw.go.jp/toukei/list/20-19-1.html (2015.12.01) (in Japanese). Ministry of Health, Labor and Welfare:Comprehensive Survey of Living Conditions 2007.
Nakamura K. The concept and treatment of locomotive syndrome: its acceptance and spread in Japan. J Orthop Sci. 2011;16:489–91.
Eiichi A, Nobuya I, Toyoshi I, Kazunori U, Yukio T, Jirou N, et al.Treatment Guide for Diabetes 2014–2015, Edited by Japan Diabetes Society. Bunkodo; 2014. p 24 (in Japanese).
Iizuka Y, Iizuka H, Mieda T, Tajika T, Yamamoto A, Takagishi K. Association between “loco-check” and EuroQol, a comprehensive instrument for assessing health-related quality of life:a study of the Japanese general population. J Orthop Sci. 2014;19:786–91.
Kessler RC, Andrews G, Colpe LJ, Hiripi E, Mroczek DK, Normand SL, et al. Short screening scales to monitor population prevalences and trends in non-specific psychological distress. Psychol Med. 2002;32:959–76.
Furukawa TA, Kessler RC, Slade T, Andrews G. The performance of the K6 and K10 screening scales for psychological distress in the Australian National Survey of Mental Health and Well-Bing. Psychol Med. 2003;33:357–62.
Kessler RC, Barker PR, Colpe LJ, Epstein JF, Gfroerer JC, Hiripi E, et al. Screening for serious mental illness in the general population. Arch Gen Psychiatry. 2003;60:184–9.
EuroQol Group. EuroQol; a new facility for the measurement of health-related quality of life. Health Policy. 1990;16:199–208.
Rabin R, de Charro F. EQ-5D: a measurement of health status from the EuroQol Group. Ann Med. 2001;33:337–43.
Brooks R. EuroQol: the current state of play. Health Policy. 1996;37:53–72.
Ikeda S, Ikegami N. Health status in Japanese population: results from Japanese EuroQol study. J Health Care Soc. 1999;9:83–92.
Ikegami N, Fukuhara S, Ikeda S.QOL evaluation handbook for clinical diagnosis. Igaku Shoin; 2001. p 45–9 (in Japanese).
https://locomo-joa.jp/locomo/ (2015.12.01) (in Japanese).
https://locomo-joa.jp/check/lococheck/ (2015.12.01) (in Japanese).
Hirano K, Imagawa S, Hasegawa Y, Ito Z, Muramoto A, Ishiguro N. The influence of locomotive syndrome on health-related quality of life in a community-living population. Mod Rheumatol. 2013;23:939–44.
Saleh F, Ara F, Mumu SJ, Hafez MA. Assessment of health-related quality of life Bangladeshi patients with type 2 diabetes using the EQ-5D: a cross-sectional study. BMC Res Notes. 2015;8:497.
Porojan M, Poanta L, Dumitrascu DL. Assessing health related quality of life in diabetic patients. Rom J Intern Med. 2012;50:27–31.
Myers VH, Kramer K, McVay MA, Harris MN, Brashear MM, Johnson WD, et al. Exercise training and quality of life in individuals with type 2 diabetes: a randomized controlled trial. Diabetes Care. 2013;36:1884–90.
Ebihara C, Arai T, Fujita H, Katou G, Sinooka S, Morita Y, et al. The relationship between locomotive syndrome and quality of life of community-dwelling elderly people. Rigakuryoho Kagaku. 2013;28:569–72 (in Japanese).
Nakagoshi R, Takemasa S, Nakayama H, Mori Y. The relationship between locomotive syndrome and daily activity and health-related quality of life of the community-dwelling elderly. Rigakuryoho Kagaku. 2015;30:557–61.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare that there were no conflicts of interest in this study.
Rights and permissions
About this article
Cite this article
Asakura, R., Miyatake, N., Mochimasu, K.D. et al. Comparison of health-related quality of life between type 2 diabetic patients with and without locomotive syndrome. Environ Health Prev Med 21, 356–360 (2016). https://doi.org/10.1007/s12199-016-0537-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12199-016-0537-z