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The accumulation of healthy lifestyle behaviors prevents the incidence of chronic kidney disease (CKD) in middle-aged and older males

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Environmental Health and Preventive Medicine Aims and scope

Abstract

Aim

This study was retrospectively designed to evaluate the influence of healthy lifestyle behaviors on the incidence of chronic kidney disease (CKD) during a 5-year follow-up period in middle-aged and older males.

Methods

The subjects included 252 males without a history of cardiovascular disease, stroke, renal dysfunction and/or dialysis treatment who were not taking any medications. Their lifestyle behaviors were evaluated using a standardized self-administered questionnaire and defined as follows: (1) habitual moderate exercise, (2) daily physical activity, (3) fast walking speed, (4) slow eating speed, (5) no late-night dinner, (6) no bedtime snacking and (7) no skipping breakfast. The participants were divided into four categories, which were classified into quartile distributions according to the number of healthy lifestyle behaviors (7–6, 5, 4 and ≤3 groups).

Results

After 5 years, the incidence of CKD [estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2 and/or proteinuria] was observed in 23 subjects (9.1 %). The Kaplan–Meier survival curves showed that the cumulative incidence of CKD significantly decreased according to an increase in the number of healthy lifestyle behaviors (log-rank test: p = 0.003). According to a multivariate analysis, habitual moderate exercise [hazard ratio (HR) 0.20, 95 % confidence of interval (CI) 0.06–0.69, p = 0.011] and no bedtime snacking (HR 0.19, 95 % CI 0.08–0.48, p = 0.004) were significantly associated with the incidence of CKD.

Conclusions

These results suggest that the accumulation of healthy lifestyle behaviors, especially those related to habitual moderate exercise and no bedtime snacking, is considered to be important to reduce the risk of CKD.

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Acknowledgments

We would like to thank Drs. Masaki Munekiyo, Kazunori Mine, Tatsuhiko Kawarabayashi, Eiichi Yoshimura, Noriko Takeda, Tomoe Horita and the members of the Laboratory of Exercise Physiology and Health Care Center of Fukuoka University for their assistance with the data evaluation. We are grateful to the participants of this study. This work was performed with the support of the Fukuoka University Institute for Physical Activity via a Technology Scientific Research Budget Basic Research Grant (No. A19200049, Strategic Research Infrastructure) from the Japanese Government’s Ministry of Education, Culture, Sports, Science and Technology.

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Authors and Affiliations

  1. Department of Health Development, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu, 807-8555, Japan

    Ryoma Michishita

  2. The Fukuoka University Institute for Physical Activity, Fukuoka, Japan

    Ryoma Michishita, Takuro Matsuda, Shotaro Kawakami, Akira Kiyonaga, Hiroaki Tanaka & Yasuki Higaki

  3. Department of Rehabilitation, Fukuoka University Hospital, Fukuoka, Japan

    Takuro Matsuda

  4. Laboratory of Exercise Physiology, Faculty of Health and Sports Science, Fukuoka University, Fukuoka, Japan

    Shotaro Kawakami, Akira Kiyonaga, Hiroaki Tanaka & Yasuki Higaki

  5. Fukuoka University Health Care Center, Fukuoka, Japan

    Natsumi Morito

  6. Department of Cardiology, Fukuoka University School of Medicine, Fukuoka, Japan

    Natsumi Morito

Authors
  1. Ryoma Michishita
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  2. Takuro Matsuda
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  4. Akira Kiyonaga
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Correspondence to Ryoma Michishita.

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Michishita, R., Matsuda, T., Kawakami, S. et al. The accumulation of healthy lifestyle behaviors prevents the incidence of chronic kidney disease (CKD) in middle-aged and older males. Environ Health Prev Med 21, 129–137 (2016). https://doi.org/10.1007/s12199-016-0506-6

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  • DOI: https://doi.org/10.1007/s12199-016-0506-6

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