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Flow cytometry analysis of peripheral Tregs in patients with multiple myeloma under lenalidomide maintenance

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Fig. 1

References

  1. Minnema MC, Van der Veer MS, Aarts T, Emmelot M, Mutis T, Lokhorst HM. Lenalidomide alone or in combination with dexamethasone is highly effective in patients with relapsed multiple myeloma following allogeneic stem cell transplantation and increases the frequency of CD4+Foxp3+ T cells. Leukemia. 2009;23(3):605–7.

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Authors and Affiliations

  1. Department of Hematology and Oncology, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan

    Kenji Nozaki & Hirohiko Shibayama

  2. Department of Hematology Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan

    Yuki Fujioka

  3. Division of Cancer Immunology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan

    Yuki Fujioka & Hiroyoshi Nishikawa

  4. Department of Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan

    Daisuke Sugiyama

  5. Department of Hematology, Osaka International Cancer Institute, Osaka, Japan

    Jun Ishikawa

  6. Department of Hematology, Kawasaki Hospital, Kobe, Japan

    Masato Iida

  7. Ikeda City Hospital, Ikeda, Japan

    Masaru Shibata

  8. Department of Internal Medicine (Hematology), Toyonaka Municipal Hospital, Toyonaka, Japan

    Satoru Kosugi

Authors
  1. Kenji Nozaki
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  2. Yuki Fujioka
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  3. Daisuke Sugiyama
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  4. Jun Ishikawa
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  5. Masato Iida
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  6. Masaru Shibata
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  7. Satoru Kosugi
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  8. Hiroyoshi Nishikawa
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  9. Hirohiko Shibayama
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Contributions

DS, HN, and HS contributed to the conception and design of the study. The provision of study materials and patients was managed by JI, MI, MS, SK, and HS. All of the authors contributed to data collection and assembly. YF performed the sample analysis. Data analyses and interpretation were performed by KN, YF, and HS. KN wrote the manuscript, and all of the authors approved the final manuscript.

Corresponding author

Correspondence to Kenji Nozaki.

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Conflict of interest

Kenji Nozaki received personal fees from Chugai and Celgene, outside of this study. Hirohiko Shibayama received grants and personal fees from Takeda, Ono, Sumitomo Dainippon Pharma, Mundi Pharma, and Nippon Shinyaku; grants from Teijin, MSD, Shionogi, and Taiho; personal fees from Novartis, Janssen, Celgene, Chugai, Kyowa Kirin, Otsuka, AstraZeneca, AbbVie, Daiichi Sankyo, Fujimoto, Sanofi, Bristol-Meyers Squibb, and Pfizer, outside of this study.

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Nozaki, K., Fujioka, Y., Sugiyama, D. et al. Flow cytometry analysis of peripheral Tregs in patients with multiple myeloma under lenalidomide maintenance. Int J Hematol 113, 772–774 (2021). https://doi.org/10.1007/s12185-021-03093-y

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  • DOI: https://doi.org/10.1007/s12185-021-03093-y

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