Abstract
Background
Few interventions have effectively improved health outcomes among youth with diabetes in chronic poor metabolic control.
Purpose
This study aims to determine whether multisystemic therapy (MST), an intensive, home-based, tailored family treatment, was superior to weekly telephone support for improving regimen adherence and metabolic control among adolescents with chronic poor metabolic control.
Methods
A randomized controlled trial was conducted with 146 adolescents with types 1 or 2 diabetes. Data were collected at baseline, 7 months (treatment termination), and 12 months (6 months follow-up).
Results
Adolescents receiving MST had significantly improved metabolic control at 7 (1.01 % decrease) and 12 months (0.74 % decrease) compared to adolescents in telephone support. Parents of adolescents receiving MST reported significant improvements in adolescent adherence. However, adolescent-reported adherence was unchanged.
Conclusions
MST improved health outcomes among adolescents with chronic poor metabolic control when compared to telephone support. Home-based approaches may provide a viable means to improve access to behavioral interventions for such youth.
Similar content being viewed by others
References
Burdick J, Chase HP, Slover RH, et al. Missed insulin meal boluses and elevated hemoglobin A1c levels in children receiving insulin pump therapy. Pediatrics. 2004; 113: e221–224.
Helgeson VS, Siminerio L, Escobar O, Becker D. Predictors of metabolic control among adolescents with diabetes: A 4-year longitudinal study. J Pediatr Psychol. 2009; 34: 254–270.
Seiffge-Krenke I, Stemmler M. Coping with everyday stress and links to medical and psychosocial adaptation in diabetic adolescents. J Adolesc Heal. 2003; 33: 180–188.
Menzin J, Langley-Hawthorne C, Friedman M, Boulanger L, Cavanaugh R. Potential short-term economic benefits of improved glycemic control: A managed care perspective. Diabetes Care. 2001; 24: 51–55.
Menzin J, Korn JR, Cohen J, et al. Relationship between glycemic control and diabetes-related hospital costs in patients with type 1 and type 2 diabetes mellitus. J Manag Care Pharm. 2010; 16: 264–275.
Grey M, Boland EA, Davidson M, Li J, Tamborlane WV. Coping skills training for youth with diabetes mellitus has long-lasting effects on metabolic control and quality of life. J Pediatr. 2000; 137: 107–113.
Anderson BJ, Brackett J, Ho J, Laffel LM. An office-based intervention to maintain parent–adolescent teamwork in diabetes management. Impact on parent involvement, family conflict, and subsequent glycemic control. Diabetes Care. 1999; 22: 713–721
Laffel LMB, Vangsness L, Connell A, et al.. Impact of ambulatory, family-focused teamwork intervention on glycemic control in youth with type 1 diabetes. J Pediatr. 2003; 142: 409–416.
Nansel TR, Iannotti RJ, Simons-Morton BG, et al. Long-Term Maintenance of Treatment Outcomes: Diabetes Personal Trainer Intervention for Youth With Type 1 Diabetes. Diabetes Care. 2009; 32: 807–809.
Channon SJ, Huws-Thomas MV, Rollnick S, et al. A multicenter randomized controlled trial of motivational interviewing in teenagers with diabetes. Diabetes Care. 2007; 30: 1390–1395.
Svoren BM, Butler D, Levine BS, Anderson BJ, Laffel LM. Reducing acute adverse outcomes in youths with type 1 diabetes: A randomized, controlled trial. Pediatrics. 2003; 112: 914–922.
Delamater AM, Jacobson AM, Anderson B, et al. Psychosocial therapies in diabetes: Report of the psychosocial therapies working group. Diabetes Care. 2001; 24: 1286–1292.
Wysocki T, Harris MA, Buckloh LM, et al. Effects of behavioral family systems therapy for diabetes on adolescents' family relationships, treatment adherence, and metabolic control. J Pediatr Psychol. 2006; 31: 928–938.
Wysocki T, Harris MA, Buckloh LM, et al. Randomized trial of behavioral family systems therapy for diabetes: Maintenance of effects on diabetes outcomes in adolescents. Diabetes Care. 2007; 30: 555–560.
Urbach SL, LaFranchi S, Lambert L, et al. Predictors of glucose control in children and adolescents with type 1 diabetes mellitus. Pediatr Diabetes. 2005; 6: 69–74.
Tershakovec AM, Kuppler K. Ethnicity, insurance type, and follow-up in a pediatric weight management program. Obes Res. 2003; 11: 17–20.
Henggeler SW. Efficacy studies to large-scale transport: The development and validation of multisystemic therapy programs. Ann Rev Clin Psychol. 2011; 7: 351–81.
Naar-King S, Podolski CL, Ellis DA, Frey MA. Social ecological model of illness management in high risk youth with type 1 diabetes. J Consult Clin Psychol. 2006; 74: 785–789.
Ellis DA, Templin T, Naar-King S, et al. Multisystemic therapy for adolescents with poorly controlled type I diabetes: Stability of treatment effects in a randomized controlled trial. J Consult Clin Psychol. 2007; 75: 168–174.
Ellis DA, Frey MA, Naar-King S, et al. The effects of multisystemic therapy on diabetes stress in adolescents with chronically poorly controlled type I diabetes: Findings from a randomized controlled trial. Pediatrics. 2005; 116: e826–e832.
Ellis DA, Yopp J, Templin T, et al. Family mediators and moderators of treatment outcomes among youths with poorly controlled type 1 diabetes: Results from a randomized controlled trial. J Pediatr Psychol. 2007; 32: 194–205.
Silverstein J, Klingensmith G, Copeland K, et al. (2005). Care of children and adolescents with type 1 diabetes: a statement of the American Diabetes Association. Diabetes Care. 2005; 28: 186–212.
Henggeler SW, Schoenwald SK, Borduin CM: Multisystemic therapy for antisocial behavior in children and adolescents (second edition). New York: The Guilford Press, 2009.
Ellis DA, Frey MA, Naar-King S, et al. Use of multisystemic therapy to improve regimen adherence among adolescents with type 1 diabetes in chronic poor metabolic control: A randomized controlled trial. Diabetes Care. 2005; 28: 1604–1610.
Ellis DA, Naar-King S, Cunningham PB, Secord E. Use of multisystemic therapy to improve antiretroviral adherence and health outcomes in HIV-infected pediatric patients: Evaluation of a pilot program. AIDS Patient Care STDs. 2006; 20: 112–121.
Naar-King S, Ellis D, Kolmodin K, Cunningham P, Secord E. Feasibility of adapting multisystemic therapy to improve illness management behaviors and reduce asthma morbidity in high risk African American youth: A case series. J Child Fam Stud. 2009; 18: 564–573.
Henggeler SW, Halliday-Boykins CA, Cunningham PB, et al. Juvenile drug court: Enhancing outcomes by integrating evidence-based treatments. J Consult Clin Psychol. 2006; 74: 42.
Ellis DA, Naar-King S, Templin T, Frey MA, Cunningham PB. Improving health outcomes among youth with poorly controlled type 1 diabetes: The role of treatment fidelity in a randomized clinical trial of multisystemic therapy. J Fam Psychol. 2007; 21: 363–371.
Safer DL, Hugo EM. Designing a control for a behavioral group therapy. Behav Ther. 2006; 37: 120–130.
Frey MA, Ellis DA, Naar-King S, Greger N. Diabetes management of adolescents in poor metabolic control. Diabetes Educ. 2004; 30: 647–657.
Frey MA, Denyes MJ. Health and illness self-care in adolescents with IDDM: A test of Orem's theory. Adv Nurs Sci. 1989; 12: 67–75.
Schilling LS, Grey M, Knafl K: A review of measures of self-management of type 1 diabetes by youth and their parents. Diabetes Educ. 2002; 28: 796–808.
Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med. 2000, 342: 381–389.
White NH, Cleary PA, Dahms W, Goldstein D, Malone J, Tamborlane WV, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group (2001) Beneficial effects of intensive therapy of diabetes during adolescence: Outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT). J Pediatr 139: 804–812.
Nunn E, King B, Smart C, Anderson D. A randomized controlled trial of telephone calls to young patients with poorly controlled type 1 diabetes. Pediatr Diabetes. 2006; 7: 254–259.
Martin CL, Albers J, Herman WH, et al. Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion. Diabetes Care. 2006; 29: 340–344.
Ellis D, Naar-King S, Templin T, et al. Multisystemic therapy for adolescents with poorly controlled type 1 diabetes: Reduced diabetic ketoacidosis admissions and related costs over 24 months. Diabetes Care. 2008; 31: 1746–1747.
Acknowledgments
This project was supported by grant #R01 DK59067 from the National Institute of Diabetes, Digestive and Kidney Diseases. The authors would like to acknowledge Yuanjing Ren for her assistance with preparation of data for use in the analyses.
Conflict of Interest Statement
Three of the authors are board members of Evidence Based Services, which has a licensing agreement with MST Services, LLC, for dissemination of multisystemic therapy treatment technology. There are no other potential author conflicts of interest.
Author information
Authors and Affiliations
Corresponding author
About this article
Cite this article
Ellis, D.A., Naar-King, S., Chen, X. et al. Multisystemic Therapy Compared to Telephone Support for Youth with Poorly Controlled Diabetes: Findings from a Randomized Controlled Trial. ann. behav. med. 44, 207–215 (2012). https://doi.org/10.1007/s12160-012-9378-1
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12160-012-9378-1