Abstract
Background
There is increasing recognition of mindfulness and mindfulness training as a way to decrease stress and increase psychological functioning.
Purpose
The aims of this study were to examine the effects of mindfulness stress reduction training on perceived stress and psychological well-being and to examine if changes in mindfulness mediate intervention effects on these outcomes.
Methods
Seventy women and one man with a previous cancer diagnosis (mean age 51.8 years, standard deviation = 9.86) were randomized into an intervention group or a wait-list control group. The intervention consisted of an 8-week mindfulness training course.
Results
Compared to participants in the control group, participants in the mindfulness training group had significantly decreased perceived stress and posttraumatic avoidance symptoms and increased positive states of mind. Those who participated in the intervention reported a significant increase in scores on the five-facet mindfulness questionnaire (FFMQ) when compared to controls. The increase in FFMQ score mediated the effects of the intervention on perceived stress, posttraumatic avoidance symptoms, and positive states of mind.
Conclusions
This study indicates that the improvements in psychological well-being resulting from mindfulness stress reduction training can potentially be explained by increased levels of mindfulness as measured with the FFMQ. The importance of these findings for future research in the field of mindfulness is discussed.
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References
Brown KW, Ryan RM, Creswell JD. Mindfulness: Theoretical foundations and evidence for its salutary effects. Psychol Inq. 2007; 18: 211–237.
Carlson LE, Garland SN. Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients. Int J Behav Med. 2005; 12: 278–285.
Carlson LE, Speca M, Patel KD, Goodey E. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med. 2003; 65: 571–581.
Carlson LE, Speca M, Patel KD, Goodey E. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. Psychoneuroendocrinology. 2004; 29: 448–474.
Grossman P, Niemann L, Schmidt S, Walach H. Mindfulness-based stress reduction and health benefits. A meta-analysis. J Psychosom Res. 2004; 57: 35–43.
Kabat-Zinn J. Full Catastrophe Living: Using the Wisdom of Your Body and Mind to Face Stress, Pain and Illness. New York: Delacourt; 1990.
Ott MJ, Norris RL, Bauer-Wu SM. Mindfulness meditation for oncology patients: A discussion and critical review. Integr Cancer Ther. 2006; 5: 98–108.
Shapiro SL, Bootzin RR, Figueredo AJ, Lopez AM, Schwartz GE. The efficacy of mindfulness-based stress reduction in the treatment of sleep disturbance in women with breast cancer: An exploratory study. J Psychosom Res. 2003; 54: 85–91.
Smith JE, Richardson J, Hoffman C, Pilkington K. Mindfulness-based stress reduction as supportive therapy in cancer care: Systematic review. J Adv Nurs. 2005; 52: 315–327.
Bishop SR, Lau M, Shapiro S, et al. Mindfulness: A proposed operational definition. Clin Psychol Sci Pract. 2004; 11: 230–241.
Segal ZV, Williams JMG, Teasdale JD. Mindfulness-Based Cognitive Therapy for Depression. New York: Guilford; 2002.
Linehan MM. Skills Training Manual for Treating Borderline Personality Disorder. New York: Guilford; 1993.
Hayes SC. Get Out of Your Mind & Into Your Life: The New Acceptance & Commitment Therapy. Oakland: New Harbinger; 2005.
Baer RA, Smith GT, Hopkins J, Krietemeyer J, Toney L. Using self-report assessment methods to explore facets of mindfulness. Assessment. 2006; 13: 27–45.
Bishop SR. What do we really know about mindfulness-based stress reduction? Psychosom Med. 2002; 64: 71–83.
Shapiro SL, Carlson LE, Astin JA, Freedman B. Mechanisms of mindfulness. J Clin Psychol. 2006; 62: 373–386.
Carlson LE, Ursuliak Z, Goodey E, Angen M, Speca M. The effects of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients: 6-month follow-up. Support Care Cancer. 2001; 9: 112–123.
Speca M, Carlson LE, Goodey E, Angen M. A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients. Psychosom Med. 2000; 62: 613–622.
Lengacher CA, Johnson-Mallard V, Post-White J, et al. Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology. 2009; 18: 1261–1272.
Ledesma D, Kumano H. Mindfulness-based stress reduction and cancer: A meta-analysis. Psychooncology. 2009; 18: 571–579.
Nyklicek I, Kuijpers KF. Effects of mindfulness-based stress reduction intervention on psychological well-being and quality of life: Is increased mindfulness indeed the mechanism? Ann Behav Med. 2008; 35: 331–340.
Shapiro SL, Oman D, Thoresen CE, Plante TG, Flinders T. Cultivating mindfulness: Effects on well-being. J Clin Psychol. 2008; 64: 840–862.
Smith MY, Redd WH, Peyser C, Vogl D. Post-traumatic stress disorder in cancer: A review. Psychooncology. 1999; 8: 521–537.
SPSS Inc. SPSS 15.0 for Windows. Chicago: SPSS Inc.; 1999.
Baer RA, Smith GT, Lykins E, et al. Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment. 2008; 15: 329–342.
Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983; 24: 385–396.
Bjelland I, Dahl AA, Haug TT, Neckelmann D. The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res. 2002; 52: 69–77.
Adler NE, Horowitz M, Garcia A, Moyer A. Additional validation of a scale to assess positive states of mind. Psychosom Med. 1998; 60: 26–32.
Horowitz M, Adler N, Kegeles S. A scale for measuring the occurrence of positive states of mind: A preliminary report. Psychosom Med. 1988; 50: 477–483.
Horowitz M, Wilner N, Alvarex W. Impact of event scale: A measure of subjective stress. Psychosom Med. 1979; 41: 209–218.
Cohen J. Statistical Power Analysis for the Behavioral Sciences. Hillsdale: L. Erlbaum; 1988.
Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986; 51: 1173–1182.
Witek-Janusek L, Albuquerque K, Chroniak KR, et al. Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun. 2008; 22: 969–981.
Fredrickson BL. The broaden-and-build theory of positive emotions. Philos Trans R Soc Lond B Biol Sci. 2004; 359: 1367–1378.
Folkman S. The case for positive emotions in the stress process. Anxiety Stress Coping. 2008; 21: 3–14.
Moskowitz JT. Positive affect predicts lower risk of AIDS mortality. Psychosom Med. 2003; 65: 620–626.
Danner DD, Snowdon DA, Friesen WV. Positive emotions in early life and longevity: Findings from the nun study. J Pers Soc Psychol. 2001; 80: 804–813.
Ostir GV, Markides KS, Black SA, Goodwin JS. Emotional well-being predicts subsequent functional independence and survival. J Am Geriatr Soc. 2000; 48: 473–478.
Ostir GV, Markides KS, Peek MK, Goodwin JS. The association between emotional well-being and the incidence of stroke in older adults. Psychosom Med. 2001; 63: 210–215.
Moskowitz JT, Epel ES, Acree M. Positive affect uniquely predicts lower risk of mortality in people with diabetes. Health Psychol. 2008; 27: S73–S82.
Shao J, Zhong B. Last observation carry-forward and last observation analysis. Stat Med. 2003; 22: 2429–2441.
Grossman P. On measuring mindfulness in psychosomatic and psychological research. J Psychosom Res. 2008; 64: 405–408.
Acknowledgements
This research was funded by a research grant from the Osher Center for Integrative Medicine at the Karolinska Institute, Sweden. Richard Bränström is funded by research grants from the Swedish Council for Working Life and Social Research (nos. 2006-1264 and 2006-0069) and Center for Health Care Science at the Karolinska Institute, Sweden (no. 2008-4737).
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Bränström, R., Kvillemo, P., Brandberg, Y. et al. Self-report Mindfulness as a Mediator of Psychological Well-being in a Stress Reduction Intervention for Cancer Patients—A Randomized Study. ann. behav. med. 39, 151–161 (2010). https://doi.org/10.1007/s12160-010-9168-6
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DOI: https://doi.org/10.1007/s12160-010-9168-6