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Does the Relationship Between Physical Activity and Quality of Life Differ Based on Generic Versus Disease-Targeted Instruments?

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Annals of Behavioral Medicine

Abstract

Background

There has been an increased interest in the study of physical activity and its relationship with quality of life (QOL) and health-related quality of life (HRQL) in chronic disease conditions. The investigations have used either generic or disease-targeted instruments for measuring QOL and HRQL, but have not examined differences in the associations as a function of the types of instruments.

Purpose

The present study examined the associations among physical activity, QOL, and HRQL using generic and disease-targeted instruments in persons with multiple sclerosis (MS).

Methods

Participants were 292 individuals with MS who wore an accelerometer for 7 days and then completed the Godin Leisure-Time Exercise Questionnaire (GLTEQ), Multiple Sclerosis Impact Scale-29 (MSIS-29), Leeds Multiple Sclerosis Quality of Life Scale (LMSQOL), Short Form-12 Health Survey (SF-12), and Satisfaction With Life Scale (SWLS).

Results

Accelerometer counts and GLTEQ scores had similarly sized correlations with scores from generic (SF-12) and the disease-specific (MSIS-29) measures of HRQL and generic (SWLS) and the disease-specific (LMSQOL) measures of QOL. Path analysis indicated a similar pattern of directional relationships between accelerometer counts and GLTEQ scores with physical and mental HRQL and, in turn, physical and mental HRQL with QOL using generic and disease-targeted instruments.

Conclusions

Our results suggest that in cross-sectional analysis, physical activity is similarly related with QOL and HRQL using generic and disease-targeted instruments in persons with MS.

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Authors and Affiliations

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Correspondence to Robert W. Motl Ph.D..

Additional information

Funded by the National Institute of Neurological Diseases and Stroke (NS054050).

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Motl, R.W., McAuley, E., Snook, E.M. et al. Does the Relationship Between Physical Activity and Quality of Life Differ Based on Generic Versus Disease-Targeted Instruments?. ann. behav. med. 36, 93–99 (2008). https://doi.org/10.1007/s12160-008-9049-4

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  • DOI: https://doi.org/10.1007/s12160-008-9049-4

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