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Soft Tissue Special Issue: Gnathic Fibro-Osseous Lesions and Osteosarcoma

  • Special Issue: Soft Tissue
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Abstract

Gnathic fibro-osseous lesions are a diverse group of disease processes which share overlapping microscopic features characterized by fibroblastic stroma with variable cellularity and a range of bone forming pathological processes leading to woven, sclerotic and cementum-like structures. Some of the lesions are unique to craniofacial location and a combination of clinical, radiological and pathological correlation is often necessary for diagnostic accuracy. Gnathic osteosarcomas are rare tumors with differences in age distribution and behavior as compared to osteosarcoma of long bones. This review will discuss the clinicopathological and radiological features of gnathic fibro-osseous lesions and osteosarcoma with updates on current genetics and molecular pathogenesis.

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Authors and Affiliations

  1. Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA

    Meera Hameed

  2. University of California, San Francisco, San Francisco, USA

    Andrew E. Horvai & Richard C. K. Jordan

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  1. Meera Hameed
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  2. Andrew E. Horvai
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Hameed, M., Horvai, A.E. & Jordan, R.C.K. Soft Tissue Special Issue: Gnathic Fibro-Osseous Lesions and Osteosarcoma. Head and Neck Pathol 14, 70–82 (2020). https://doi.org/10.1007/s12105-019-01094-2

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