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Exclusive Primary Lesion of Oral Leishmaniasis with Immunohistochemical Diagnosis

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Abstract

A case of oral leishmaniasis without cutaneous involvement affecting the upper alveolar ridge mucosa/gingiva and the hard palate is reported in a 41-year-old Brazilian man. Microscopic examination disclosed scarce amastigotes and the definitive diagnosis was facilitated by immunohistochemical analysis. The clinical presentation of this lesion is unusual and underlies the importance of considering leishmaniasis in the differential diagnosis of oral lesions, especially in endemic areas. A literature review of the cases of mucosal leishmaniasis with exclusive primary lesions of the oral mucosa was also performed.

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Acknowledgments

This work was supported by the State of São Paulo Research Foundation (FAPESP), and the State of Minas Gerais Research Foundation (FAPEMIG).

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Authors and Affiliations

  1. Department of Dentistry, Clinical Stomatology, Federal University of the Jequitinhonha and Mucuri Valleys, Rua da Glória 187, Diamantina, Minas Gerais, CEP: 39100-000, Brazil

    Tatiana Fernandes Araujo Almeida, Esmeralda Maria da Silveira, Cássio Roberto Rocha dos Santos & Ana Terezinha Marques Mesquita

  2. Oral Pathology, Department of Stomatology, Public Oral Health and Forensic Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil

    Jorge Esquiche León

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  1. Tatiana Fernandes Araujo Almeida
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  2. Esmeralda Maria da Silveira
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Correspondence to Tatiana Fernandes Araujo Almeida.

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Almeida, T.F.A., da Silveira, E.M., dos Santos, C.R.R. et al. Exclusive Primary Lesion of Oral Leishmaniasis with Immunohistochemical Diagnosis. Head and Neck Pathol 10, 533–537 (2016). https://doi.org/10.1007/s12105-016-0732-7

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  • DOI: https://doi.org/10.1007/s12105-016-0732-7

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