Abstract
Solitary fibrous tumor (SFT) is rare mesenchymal neoplasm that has been originally and most often documented in the pleura. Recently, the ubiquitous nature of the SFT has been recognized with reports of involvement of numerous sites all over the body, i.e, upper respiratory tract, breast, somatic tissue, mediastinum, head, and neck, etc. The diagnosis of SFT still remains an enigma in our field. Furthermore, malignant SFT is extremely rare and only two cases have been reported in the oral cavity till date. Here, we present a rare case report of an aggressive solitary fibrous tumor which presented as a palatal mass and extended throughout the middle cranial fossa and exhibited features of malignancy.
References
Hanau CA, Miettinen M. Solitary fibrous tumor: histological and immunohistochemical spectrum of benign and malignant variants presenting at different sites. Hum Pathol. 1995;26:440–9. doi:10.1016/0046-8177(95)90147-7.
Perez-Ordonez B, Koutlas IG, Strich E, et al. Solitary fibrous tumor of the oral cavity: an uncommon location of a ubiquitous neoplasm. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;87:589–93. doi:10.1016/S1079-2104(99)70139-3.
Alawi F, Stratton D, Freedman PD, et al. Solitary fibrous tumor of the oral soft tissues. A clinicopathologic and immunohistochemical study of 16 cases. Am J Surg Pathol. 2001;25(7):900–10. doi:10.1097/00000478-200107000-00008.
Lukinmaa PL, Hietanen J, Warfvinge G, et al. Solitary fibrous tumor of the oral cavity: clinicopathological and immunohistochemical characterization of three cases. J Oral Pathol Med. 2000;29:186–92. doi:10.1034/j.1600-0714.2000.290407.x.
Weiss SW and Goldblum JR, editors. Enzinger and Weiss’s soft tissue tumors. 5th ed. USA: Mosby Elsevier; 2008. p. 1121–36.
Shnayder Y, Greenfield BJ, Oweity T, et al. Malignant solitary fibrous tumor of the tongue. Am J Otolaryngol. 2003;24:246–9. doi:10.1016/S0196-0709(03)00007-3.
Ogawa I, Sato S, Kudo Y, et al. Solitary fibrous tumour with malignant potential arising in sublingual gland. Pathol Int. 2003;53:40–5. doi:10.1046/j.1440-1827.2003.01425.x.
Chan JKC. Solitary fibrous tumor—everywhere, and a diagnosis in vogue. Histopathology. 1997;31:568–76. doi:10.1046/j.1365-2559.1997.2400897.x.
Vargas PA, Alves FA, Lopes MA, et al. Solitary fibrous tumor of the mouth: report of two cases involving the tongue and cheek. Oral Dis. 2002;8:111–5. doi:10.1034/j.1601-0825.2002.1c769.x.
Marcarenco RS, Bacchi CE, Domingues MAC. Solitary fibrous tumor with atypical histological features occurring in the palatine tonsil: an uncommon neoplasm in an uncommon site. J Oral Pathol Med. 2006;35:602–5. doi:10.1111/j.1600-0714.2006.00460.x.
Ganly I, Patel SG, Stambuk HE, et al. Solitary fibrous tumors of the head and neck. A clinicopathologic and radiologic review. Arch Otolaryngol Head Neck Surg. 2006;132:517–25. doi:10.1001/archotol.132.5.517.
Jham BC, Porcaro Salles JM, Arantes Soares JM, et al. Solitary fibrous tumor of the buccal mucosa: case report and review of literature. Br J Oral Maxillofac Surg. 2007;45:323–5. doi:10.1016/j.bjoms.2005.11.012.
Iwai S, Nakazawa M, Yoshikawa F, et al. Solitary fibrous tumor of the buccal mucosa: report of a case with immunohistochemical studies. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:461–5. doi:10.1016/S1079-2104(99)70062-4.
Fusconi M, Ciofalo A, Greco A, et al. Solitary fibrous tumor of the oral cavity: case report and pathologic consideration. J Oral Maxillofac Surg. 2008;66:530–4. doi:10.1016/j.joms.2007.08.019.
Piattelli A, Fioroni M, Rubini C. Solitary fibrous tumor of the tongue. Oral Oncol. 1998;34:431–4. doi:10.1016/S1368-8375(98)00042-6.
Gengler C, Guillou L. Solitary fibrous tumor and haemangiopericytoma: evolution of a concept. Histopathology. 2006;48:63–74. doi:10.1111/j.1365-2559.2005.02290.x.
Kim TA, Brunberg JA, Pearson JP, et al. Solitary fibrous tumor of the paranasal sinuses: CT and MR appearance. AJNR Am J Neuroradiol. 1996;17:1767–72.
England DM, Hochholzer L, Mc Carthy MJ. Localised benign and malignant fibrous tumours of pleura: a clinicopathologic review of 223 cases. Am J Surg Pathol. 1989;13:640–58. doi:10.1097/00000478-198908000-00003.
Galie M, Tieghi R, Cavazzini L, et al. Solitary fibrous tumor of orbit: a case report. Int J Oral Maxillofac Surg. 2005;34:331–3. doi:10.1016/j.ijom.2004.05.011.
Guillou L, Coindre JM, Bonichon F, et al. Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma. J Clin Oncol. 1997;15:350–62.
Folk GS, Williams SB, Foss RB, et al. Oral and maxillofacial sclerosing epithelioid fibroscarcoma: report of five cases. Head Neck Pathol. 2007;1:13–20. doi:10.1007/s12105-007-0002-9.
Muzio LL, Mascolo M, Capodiferro S, et al. Solitary fibrous tumor of the oral cavity: the need for an extensive sampling for a correct diagnosis. J Oral Pathol Med.. 2007;36:538–42.
Eversole LR, Christensen R, Ficarra G, et al. Nodular fascitis and solitary fibrous tumor of the oral region. Tumors of fibroblast heterogeneity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;87:471–6. doi:10.1016/S1079-2104(99)70247-7.
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Vimi, S., Punnya, V.A., Kaveri, H. et al. An Aggressive Solitary Fibrous Tumor with Evidence of Malignancy: A Rare Case Report. Head and Neck Pathol 2, 236–241 (2008). https://doi.org/10.1007/s12105-008-0073-2
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DOI: https://doi.org/10.1007/s12105-008-0073-2