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Rotavirus Diarrhea and its Determinants Among Under-Five Children Admitted in a Tertiary Care Hospital of Southern Haryana, India

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Abstract

Objective

To estimate the prevalence of rotavirus diarrhea and its demographic, social, and clinical characteristics among children less than five years of age admitted in a rural tertiary care institute.

Methods

This prospective hospital-based observational study was carried out during February 2016 to June 2019. Diarrheal admissions of children aged 0–59 mo were screened and those who met the inclusion criteria were included in the study. Sociodemographic and clinical information was collected using a case report form. Stool samples were collected within 48 h of admission and transported in cold chain every month to the referral laboratory situated at Christian Medical College for testing.

Results

Among the children admitted with acute diarrhea, 148 (11.02%) were positive for rotavirus in the study. As per Vesikari scoring system, around three fourth (76.2%) of children were having severe or very severe diarrhea. Severity of diarrhea was more among rotavirus positive cases as assessed by the Vesikari scoring system. The rotavirus diarrhea showed a peak during November to February.

Conclusion

Rotavirus diarrhea is an issue of public health importance, particularly due to its association with the severe diarrhea. As evidenced from similar settings in the world, rotavirus vaccine introduction and increased coverage is the most important strategy towards prevention and control of rotavirus diarrhea.

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Acknowledgements

The authors acknowledge the support of Indian Council of Medical Research, New Delhi; Ministry of Health and Family Welfare, Government of India and the Government of Haryana. The authors thank the team at Christian Medical College, Vellore for support, and the children and families for participation.

Funding

This project was funded by grants from the Bill and Melinda Gates Foundation to the Centers for Disease Control and Prevention (CDC), Atlanta, USA (subcontract to Christian Medical College, Vellore grant no MOA#871-15SC) and the Translational Health Science and Technology Institute, Faridabad, India (grant no OPP1165083).

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Authors and Affiliations

  1. Department of Pediatrics, All India Institute of Medical Sciences, Raipur, India

    Anil Kumar Goel

  2. Department of Community Medicine, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Nuh, Haryana, 122107, India

    Suraj Chawla

  3. Department of Pediatrics, Shaheed Hasan Khan Mewati Government Medical College, Nalhar, Nuh, Haryana, India

    Arti Dhingra

  4. Department of GI Sciences, The Wellcome Trust Research Laboratory, Christian Medical College, Vellore, India

    Varunkumar Thiyagarajan & Nayana P. Nair

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  1. Anil Kumar Goel
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Contributions

AKG and SC conceptualized and designed the study; SC and AKG collected the data and drafted the paper; AD and AKG supervised the laboratory work and provided critical inputs; VT and NPN cleaned and analyzed the data. All authors approved the final manuscript. SC will act as guarantor for this paper.

Corresponding author

Correspondence to Suraj Chawla.

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Ethical Clearance

The study was approved by the institutional ethics committee of SHKM Government Medical College, Nalhar, Haryana.

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Goel, A.K., Chawla, S., Dhingra, A. et al. Rotavirus Diarrhea and its Determinants Among Under-Five Children Admitted in a Tertiary Care Hospital of Southern Haryana, India. Indian J Pediatr 88 (Suppl 1), 16–21 (2021). https://doi.org/10.1007/s12098-020-03616-1

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