Abstract
Objective
Childhood obesity is associated with unfavorable lipid profile. Obese children have increased risk of development of coronary heart disease (CHD) in adult life. There is lack of data on association of dyslipidemia with obesity in children from India, hence, the present investigation was undertaken.
Methods
Study was conducted in NCT of Delhi. Thirty schools in each of the 3 socio economic groups i.e., LIG, MIG and HIG were selected. From each school, 170 children were included in the survey. A total of 16,585 children were studied. Anthropometric measurements of weight and height were taken using standard methodology Four hundred and fifty one obese children (cases) were identified using IOTF classification. Equal number of children, matched for age, sex and socio-economic status, with optimal body weight were selected as control. The blood samples were collected for lipid profile estimation. Same investigations were undertaken, both in cases and controls.
Results
In obese children, mean total cholesterol, triglyceride and LDL-C levels were significantly higher as compared to their matched controls (p < 0.001). BMI was significantly correlated with lipid profile.
Conclusions
Obesity amongst children was associated with unfavorable lipid profile.
Similar content being viewed by others
References
Castelli WP, Garrison MS, Wilson PW, Abbott RD, Kalousdian S, Kannel WB. Incidence of coronary heart diseases and lipoprotein cholesterol levels: the Framingham study. JAMA. 1986;256:2835–8.
Lauer RM, Lee J, Clarke WR. Factors affecting the relationship between childhood and adult cholesterol levels: the Muscatine study. Pediatrics. 1988;82:309–18.
Garcia RE, Moodie DS. Routine cholesterol surveillance in childhood. Pediatrics. 1989;84:751–5.
Wong ND, Bassin S, Deitrick R. Relationship of blood lipids to body composition and family medical history in an ethnically diverse school aged population. Ethn Dis. 1991;1:351–63.
Davidson DM, VanCamp J, Iftner CA, Landry SM, Bradley BJ, Wong ND. Family history fails to detect the majority of children with high capillary blood total cholesterol. J Sch Health. 1991;61:75–80.
Cole JC, Mary CB, Katherine MF, William HD. Establishing a standard definition for child overweight and obesity worldwide: international survey. Br Med J. 2000;320:1240–3.
WHO. Physical status: The use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organisation Technical Report Series 854. Geneva: WHO; 1995. p. 427–30.
Friewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of preparative ultra centrifuge. Clin Chem. 1972;18:499–502.
National Cholesterol Education Program. Report of the expert panel on blood cholesterol levels in children and adolescents. Pediatrics. 1992;89:525–84.
Garces C, Guisado GJ, Benavente M et al. Obesity in Spanish school children: relationship with lipid profile and insulin resistance. Obes Res. 2005;13:959–63.
Dubey S, Kabra M, Bajpai A et al. Serum leptin levels in obese Indian children: relation to clinical and biochemical parameters. Indian Pediatr. 2007;44:257–62.
Mitra A, Singh S, Devidayal, Khullar M. Serum lipids in north Indian children treated for Kawasaki disease. Int Heart J. 2005;46:811–7.
Chu NF, Rimm EB, Wang DJ, Liou HS, Shieh SM. Clustering of cardiovascular disease risk factors among obese school children: the Taipei children heart study. Am J Clin Nutr. 1998;67:1141–6.
Semiz S, Ozgoren E, Sabir N, Semiz E. Body fat distribution in childhood obesity: association with metabolic risk factors. Indian Pediatr. 2008;45:457–62.
Friedland O, Memet D, Gorodnitsky N, Wolach BM, Eliakim A. Obesity and lipid profile in children and adolescents. J Pediatr Endocrinol Metab. 2002;15:1011–6.
Kelishadi R, Pour MH, Sarraf-Zadegan N et al. Obesity and associated modifiable environment factors in Iranian adolescents: Isfahan healthy program-heart health promotion from childhood. Pediatr Int. 2003;45:435–42.
Vizcaino VM, Aguilar FS, Martinez MS, Lopez MS, Gutierrez RF, Rodriguez-Artalejo F. Association of adiposity measures with blood lipids and blood pressure in children aged 8–11 years. Acta Pediatr. 2007;96:1338–42.
Acknowledgements
The study was financially supported by Division of Non-Communicable Diseases, Indian Council of Medical Research, New Delhi Vide Research Project Number 5/4/1-2/2003-NCD-II.
Contributions
St Kr; Data collection and report writing, U Kl; Study Designing and Supervising
Conflict of Interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kaur, S., Kapil, U. Dyslipidemia amongst Obese Children in National Capital Territory (NCT) of Delhi. Indian J Pediatr 78, 55–57 (2011). https://doi.org/10.1007/s12098-010-0263-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-010-0263-2