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Laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP)

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Abstract

Objective

To discuss and evaluate the safety and value of laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP).

Methods

From March 2010 to June 2015, 38 cases were retrospectively analyzed and divided into 2 groups, of which 17 cases used laparoscopy adjuvant total colorectal resection, and 21 cases used conventional laparotomy. Clinical data were obtained, and the safety and prognosis were observed.

Results

Seventeen cases using laparoscopy adjuvant total colorectal resection achieved success with no conversion to laparotomy and intraoperative complications. There was no significant difference in operation time between the two groups. There were significant differences in blood loss, the length of incision, postoperative recovery time of intestinal function and postoperative hospital stay between the two groups (P < 0.05). The trauma in laparoscopy group was less, and could recover faster, and there was no significant difference in complications between the two groups. In addition, there were no recurrence, distant metastasis and death in the follow-up period from 6 to 56 months.

Conclusion

Laparoscopy adjuvant total colorectal resection is more safe and feasible, which has minimal invasion and can recover fast.

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Author notes

  1. Z. Zhang and D. Wang These authors contributed equally to this manuscript.

Authors and Affiliations

  1. Department of Colorectal Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Tianjin, 300121, People’s Republic of China

    Z. Zhang, C. Xu, Y. Yu, Y. Li & X. Zhang

  2. Department of Pathology, Tianjin Medical University General Hospital, Tianjin, 300052, China

    D. Wang

Authors
  1. Z. Zhang
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  2. D. Wang
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  3. C. Xu
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  4. Y. Yu
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  5. Y. Li
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Corresponding author

Correspondence to X. Zhang.

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Conflict of interest

The authors have no actual or potential conflicts of interest to declare.

Ethics approval

This study was approved by the hospital ethics committee.

Informed consent

All patients gave informed consent.

Financial support

This study was supported by the Foundation of Tianjin Science and Technology Commission (No. 17JCQNJC13000) and the Foundation of Tianjin Union Medical Center (2016YJ029).

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Zhang, Z., Wang, D., Xu, C. et al. Laparoscopy adjuvant total colorectal resection for the treatment of familial adenomatous polyposis (FAP). Clin Transl Oncol 21, 753–759 (2019). https://doi.org/10.1007/s12094-018-1979-0

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  • DOI: https://doi.org/10.1007/s12094-018-1979-0

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