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The Starbuck stops here: it’s a Smad world

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Journal of Cell Communication and Signaling Aims and scope

Abstract

A recent study by Gressner and colleagues suggested caffeine may block CCN2 expression in hepatic cells. This commentary briefly summarizes these observations.

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References

  • Gressner OA, Lahme B, Rehbein K, Siluschek M, Weiskirchen R, Gressner AM (2008). Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. J Hepatol (in press)

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Authors and Affiliations

  1. CIHR Group in Skeletal Development and Remodeling, Division of Oral Biology and Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Dental Sciences Building, University of Western Ontario, London, ON, N6A 5C1, Canada

    Andrew Leask

Authors
  1. Andrew Leask
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Correspondence to Andrew Leask.

Additional information

This commentary also appears online under Newsletter section of the ICCNS Website at http://ccnsociety.com.

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Leask, A. The Starbuck stops here: it’s a Smad world. J. Cell Commun. Signal. 2, 1–2 (2008). https://doi.org/10.1007/s12079-008-0025-3

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  • DOI: https://doi.org/10.1007/s12079-008-0025-3

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