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Efficacy of Vitamin D Supplementation in Allergic Rhinitis

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Allergic Rhinitis is one of the most commonly recognised rhinitis globally. Though its not a life threatening entity but it is associated with severe impairment of quality of life along with substantial financial burden on patient. There has been a substantial rise in number of patients of allergic rhinitis over years and researchers worldwide have also found low levels of vitamin D in patients of allergic rhinitis. It is a randomised control trial with 87 subjects divided into two groups. Pre-treatment total nasal symptom score (TNSS) were recorded for these patients. The Group A was given intranasal steroidal spray while Group B was given vitamin D supplementation along with intranasal steroidal spray. Post treatment TNSS scores and rhinitis control assessment test scores were calculated and analysed. 38 patients had severe Vit D deficiency with average TNSS score as 11.3 while 49 patients had insufficient Vit D levels with average TNSS as 8.6. The pre-treatment TNSS score in Group A was 12.5 ± 2.68 while post-treatment score was 8.98 ± 1.009 with difference in both scores of Group A as 3.52. The pre-treatment TNSS score in Group B (fluticasone spay with Vit D) was 11.64 ± 3.09 while post-treatment score was 6.3 ± 1.45 with difference in both scores of Group A as 5.34. The post treatment RCAT in Group A and Group B was 19.72 ± 2.84 and 28.2 ± 1.53 respectively with difference between two groups as 8.48. Though Intranasal steroidal sprays are the first line of management of allergic rhinitis however vitamin D supplementation can have a role in better relief of symptoms when used in conjunction. More multi-institutional studies are encouraged to confirm the validity of results before it can be incorporated in standard treatment guidelines.

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Authors and Affiliations

  1. Sri Guru Ram Das University of Health Sciences, Amritsar, India

    Bhanu Bhardwaj & Jaskaran Singh

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  1. Bhanu Bhardwaj
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  2. Jaskaran Singh
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Correspondence to Jaskaran Singh.

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Before starting the study ethical clearance was taken from institutional ethical committee as per Declaration of Helsinki.

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Informed consent was taken by all the patients before surgery and enrolment into the study.

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Bhardwaj, B., Singh, J. Efficacy of Vitamin D Supplementation in Allergic Rhinitis. Indian J Otolaryngol Head Neck Surg 73, 152–159 (2021). https://doi.org/10.1007/s12070-020-01907-9

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